Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study
BACKGROUND: Dietary flavonoids may protect against cardiovascular disease, but evidence is still conflicting. Tea is the major source of flavonoids in Western populations. OBJECTIVE: The association of tea and flavonoid intake with incident myocardial infarction was examined in the general Dutch population. DESIGN: A longitudinal analysis was performed with the use of data from the Rotterdam Study-a population-based study of men and women aged >or=55 y. Diet was assessed at baseline (1990-1993) with a validated semiquantitative food-frequency questionnaire. The analysis included 4807 subjec... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2002 |
Schlagwörter: | *Kaempferols / *Tea / Aged / Diet / Dose-Response Relationship / Drug / Female / Flavonoids/*administration & dosage/pharmacology / Humans / Incidence / Longitudinal Studies / Male / Middle aged / Myocardial Infarction/epidemiology/etiology/mortality/*prevention & control / Netherlands / Quercetin/administration & dosage/*analogs & derivatives/pharmacology / Research Support / Non-U.S. Gov't / Risk Assessment |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-29200011 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://repub.eur.nl/pub/9892 |
BACKGROUND: Dietary flavonoids may protect against cardiovascular disease, but evidence is still conflicting. Tea is the major source of flavonoids in Western populations. OBJECTIVE: The association of tea and flavonoid intake with incident myocardial infarction was examined in the general Dutch population. DESIGN: A longitudinal analysis was performed with the use of data from the Rotterdam Study-a population-based study of men and women aged >or=55 y. Diet was assessed at baseline (1990-1993) with a validated semiquantitative food-frequency questionnaire. The analysis included 4807 subjects with no history of myocardial infarction, who were followed until 31 December 1997. Data were analyzed in a Cox regression model, with adjustment for age, sex, body mass index, smoking status, pack-years of cigarette smoking, education level, and daily intakes of alcohol, coffee, polyunsaturated fat, saturated fat, fiber, vitamin E, and total energy. RESULTS: During 5.6 y of follow-up, a total of