Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study

BACKGROUND: Dietary flavonoids may protect against cardiovascular disease, but evidence is still conflicting. Tea is the major source of flavonoids in Western populations. OBJECTIVE: The association of tea and flavonoid intake with incident myocardial infarction was examined in the general Dutch population. DESIGN: A longitudinal analysis was performed with the use of data from the Rotterdam Study-a population-based study of men and women aged >or=55 y. Diet was assessed at baseline (1990-1993) with a validated semiquantitative food-frequency questionnaire. The analysis included 4807 subjec... Mehr ...

Verfasser: Geleijnse, J.M. (Marianne)
Launer, L.J. (Lenore)
Kuip, D.A.M. (Deirdre) van der
Witteman, J.C.M. (Jacqueline)
Hofman, A. (Albert)
Dokumenttyp: Artikel
Erscheinungsdatum: 2002
Schlagwörter: *Kaempferols / *Tea / Aged / Diet / Dose-Response Relationship / Drug / Female / Flavonoids/*administration & dosage/pharmacology / Humans / Incidence / Longitudinal Studies / Male / Middle aged / Myocardial Infarction/epidemiology/etiology/mortality/*prevention & control / Netherlands / Quercetin/administration & dosage/*analogs & derivatives/pharmacology / Research Support / Non-U.S. Gov't / Risk Assessment
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29200011
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://repub.eur.nl/pub/9892

BACKGROUND: Dietary flavonoids may protect against cardiovascular disease, but evidence is still conflicting. Tea is the major source of flavonoids in Western populations. OBJECTIVE: The association of tea and flavonoid intake with incident myocardial infarction was examined in the general Dutch population. DESIGN: A longitudinal analysis was performed with the use of data from the Rotterdam Study-a population-based study of men and women aged >or=55 y. Diet was assessed at baseline (1990-1993) with a validated semiquantitative food-frequency questionnaire. The analysis included 4807 subjects with no history of myocardial infarction, who were followed until 31 December 1997. Data were analyzed in a Cox regression model, with adjustment for age, sex, body mass index, smoking status, pack-years of cigarette smoking, education level, and daily intakes of alcohol, coffee, polyunsaturated fat, saturated fat, fiber, vitamin E, and total energy. RESULTS: During 5.6 y of follow-up, a total of