Genetic susceptibility for cow’s milk allergy in Dutch children: the start of the allergic march? ...

Abstract Background Cow’s milk allergy (CMA) is the most common allergic disease in infancy. It is not clear, whether infants with CMA have an increased risk of developing other allergic diseases later in life, the so-called “allergic march”. We aimed to detect genetic associations of CMA using reported single nucleotide polymorphisms (SNP) in other allergic diseases and genetic mutations within the filaggrin (FLG) gene. Both to investigate possible causes of CMA, which also suggests an “allergic march”. Methods Thirty children from the Dutch EuroPrevall birth cohort study with CMA in infancy... Mehr ...