Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy
Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment. However, the treatment also resulted in immune reconstitution inflammatory syndrome and life-threatening immune-related adverse events. These conditions were treated with corticosteroids, leading to treatment resistance.
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| Dokumenttyp: | Artikel |
| Erscheinungsdatum: | 2022 |
| Reihe/Periodikum: | Emerging Infectious Diseases, Vol 28, Iss 1, Pp 253-256 (2022) |
| Verlag/Hrsg.: |
Centers for Disease Control and Prevention
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| Schlagwörter: | progressive multifocal leukoencephalopathy / immunotherapy / JC virus / immune reconstitution inflammatory syndrome / Belgium / viruses / Medicine / R / Infectious and parasitic diseases / RC109-216 |
| Sprache: | Englisch |
| Permalink: | https://search.fid-benelux.de/Record/base-28938397 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://doi.org/10.3201/eid2801.204809 |
