Performance of Xpert MTB/RIF Ultra for diagnosis of pulmonary and extra-pulmonary tuberculosis, one year of use in a multi-centric hospital laboratory in Brussels, Belgium
Among the challenges in controlling tuberculosis, a rapid and accurate diagnostic test for the detection of Mycobacterium tuberculosis complex ( MTB c) and its resistance to first line therapies is crucial. We evaluated the performance of the Xpert MTB/RIF Ultra assay (Xpert Ultra) for the rapid detection of MTB c and rifampicin resistance (RR) in 1120 pulmonary and 461 extra-pulmonary clinical specimens and compared it with conventional phenotypic techniques. The Xpert Ultra assay detected MTB c in 223 (14.1%) samples with an overall sensitivity and specificity, using culture as the “gold sta... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2021 |
Reihe/Periodikum: | PLOS ONE ; volume 16, issue 4, page e0249734 ; ISSN 1932-6203 |
Verlag/Hrsg.: |
Public Library of Science (PLoS)
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Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28547503 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1371/journal.pone.0249734 |