Associations between vitamin D receptor genotypes and mortality in a cohort of older Dutch individuals

Context Vitamin D receptor (VDR) polymorphisms are associated with a variety of diseases, which may translate into an effect on mortality. Objective To investigate the associations between VDR gene variants and mortality among older people. Design The analyses were conducted in a population-based, prospective cohort of the Longitudinal Aging Study Amsterdam. Adequate DNA analysis was performed in 923 men and women (≥65 years). We aimed to assess the associations between mortality and the VDR polymorphism FokI , three haplotypes of the Cdx2 and GATA polymorphisms, and three haplotypes of the Bs... Mehr ...