1
Leeuwen, Elisa, Karssen, Lennart, Deelen, J, Isaacs, Aaron, Medina-Gomez, C, Mbarek, H, Kanterakis, A, Trompet, S, Postmus, I, Verweij, N (Niek), van Enckevort, DJ, Huffman, JE, White, CC, Feitosa, MF, Bartz, TM, Manichaikul, A, Joshi, PK, Peloso, GM, Deelen, P, Dijk, Femke, Willemsen, G, de Geus, EJ, Milaneschi, Y, Penninx, BWJH, Francioli, LC, Menelaou, A, Pulit, SL, Rivadeneira, Fernando, Hofman, Bert, Oostra, Ben, Franco Duran, OH, Leach, IM, Beekman, M, de Craen, AJM, Uh, HW, Trochet, H, Hocking, LJ, Porteous, DJ, Sattar, N, Packard, CJ, Buckley, BM, Brody, JA, Bis, JC, Rotter, JI, Mychaleckyj, JC, Campbell, H, Duan, Q, Lange, LA, Wilson, JF, Hayward, C
Veröffentlicht in: Leeuwen , E , Karssen , L , Deelen , J , Isaacs , A , Medina-Gomez , C , Mbarek , H , Kanterakis , A , Trompet , S , Postmus , I , Verweij , N , van Enckevort , DJ , Huffman , JE , White , CC , Feitosa , MF , Bartz , TM , Manichaikul , A , Joshi , PK , Peloso , GM , Deelen , P , Dijk , F , Willemsen , G , de Geus , EJ , Milaneschi , Y , Penninx , BWJH , Francioli , LC , Menelaou , A , Pulit , SL , Rivadeneira , F , Hofman , B , Oostra , B , Franco Duran , OH , Leach , IM , Beekman , M , de Craen , AJM , Uh , HW , Trochet , H , Hocking , LJ , Porteous , DJ , Sattar , N , Packard , CJ , Buckley , BM , Brody , JA , Bis , JC , Rotter , JI , Mychaleckyj , JC , Campbell , H , Duan , Q , Lange , LA , Wilson , JF , Hayward , C , Polasek , O , Vitart , V , Rudan , I , Wright , AF , Rich , SS , Psaty , BM , Borecki , IB , Kearney , PM , Stott , DJ , Cupples , LA , Jukema , JW , van der Harst , P , Sijbrands , E J G , Hottenga , JJ , Uitterlinden , A , Swertz , MA , van Ommen , GJB , de Bakker , PIW , Slagboom , PE , Boomsma , DI , Wijmenga , C & Duijn , C 2015 , ' Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels ' , Nature Communications , vol. 6 . https://doi.org/10.1038/ncomms7065;
2015
Veröffentlicht in: Leeuwen , E , Karssen , L , Deelen , J , Isaacs , A , Medina-Gomez , C , Mbarek , H , Kanterakis , A , Trompet , S , Postmus , I , Verweij , N , van Enckevort , DJ , Huffman , JE , White , CC , Feitosa , MF , Bartz , TM , Manichaikul , A , Joshi , PK , Peloso , GM , Deelen , P , Dijk , F , Willemsen , G , de Geus , EJ , Milaneschi , Y , Penninx , BWJH , Francioli , LC , Menelaou , A , Pulit , SL , Rivadeneira , F , Hofman , B , Oostra , B , Franco Duran , OH , Leach , IM , Beekman , M , de Craen , AJM , Uh , HW , Trochet , H , Hocking , LJ , Porteous , DJ , Sattar , N , Packard , CJ , Buckley , BM , Brody , JA , Bis , JC , Rotter , JI , Mychaleckyj , JC , Campbell , H , Duan , Q , Lange , LA , Wilson , JF , Hayward , C , Polasek , O , Vitart , V , Rudan , I , Wright , AF , Rich , SS , Psaty , BM , Borecki , IB , Kearney , PM , Stott , DJ , Cupples , LA , Jukema , JW , van der Harst , P , Sijbrands , E J G , Hottenga , JJ , Uitterlinden , A , Swertz , MA , van Ommen , GJB , de Bakker , PIW , Slagboom , PE , Boomsma , DI , Wijmenga , C & Duijn , C 2015 , ' Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels ' , Nature Communications , vol. 6 . https://doi.org/10.1038/ncomms7065;
2015
2
Morris, R.W., Taylor, A.E., Fluharty, M.E., Bjorngaard, J.H., Asvold, B.O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L.L.N., Skaaby, T., Ahluwalia, T.S., Treur, J.L., Willemsen, G., Dale, C., Wannamethee, S.G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgard, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D.M., Kennedy, M.A., Nohr, E.A., Christiansen, L., Kyvik, K.O., Kuh, D, Watt, G., Eriksson, J.G., Whincup, P.H., Vink, J.M., Boomsma, D.I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J.W., Power, C., Hyppönen, E., Jarvelin, M.R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B.H., Hayward, C., Romundstad, P.R., Sørensen, T.I.A., Munafò, M., Sattar, N.
Veröffentlicht in: Morris , R W , Taylor , A E , Fluharty , M E , Bjorngaard , J H , Asvold , B O , Elvestad Gabrielsen , M , Campbell , A , Marioni , R , Kumari , M , Korhonen , T , Männistö , S , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Husemoen , L L N , Skaaby , T , Ahluwalia , T S , Treur , J L , Willemsen , G , Dale , C , Wannamethee , S G , Lahti , J , Palotie , A , Räikkönen , K , McConnachie , A , Padmanabhan , S , Wong , A , Dalgard , C , Paternoster , L , Ben-Shlomo , Y , Tyrrell , J , Horwood , J , Fergusson , D M , Kennedy , M A , Nohr , E A , Christiansen , L , Kyvik , K O , Kuh , D , Watt , G , Eriksson , J G , Whincup , P H , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D , Linneberg , A , Ford , I , Jukema , J W , Power , C , Hyppönen , E , Jarvelin , M R , Preisig , M , Borodulin , K , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Romundstad , P R , Sørensen , T I A , Munafò , M & Sattar , N 2015 , ' Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium ' , BMJ Open , vol. 5 , no. 8 , pp. e008808 . https://doi.org/10.1136/bmjopen-2015-008808;
2015
Veröffentlicht in: Morris , R W , Taylor , A E , Fluharty , M E , Bjorngaard , J H , Asvold , B O , Elvestad Gabrielsen , M , Campbell , A , Marioni , R , Kumari , M , Korhonen , T , Männistö , S , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Husemoen , L L N , Skaaby , T , Ahluwalia , T S , Treur , J L , Willemsen , G , Dale , C , Wannamethee , S G , Lahti , J , Palotie , A , Räikkönen , K , McConnachie , A , Padmanabhan , S , Wong , A , Dalgard , C , Paternoster , L , Ben-Shlomo , Y , Tyrrell , J , Horwood , J , Fergusson , D M , Kennedy , M A , Nohr , E A , Christiansen , L , Kyvik , K O , Kuh , D , Watt , G , Eriksson , J G , Whincup , P H , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D , Linneberg , A , Ford , I , Jukema , J W , Power , C , Hyppönen , E , Jarvelin , M R , Preisig , M , Borodulin , K , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Romundstad , P R , Sørensen , T I A , Munafò , M & Sattar , N 2015 , ' Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium ' , BMJ Open , vol. 5 , no. 8 , pp. e008808 . https://doi.org/10.1136/bmjopen-2015-008808;
2015
3
Linneberg, A., Jacobsen, R.K., Skaaby, T., Taylor, A.E., Fluharty, M.E., Jeppesen, J., Bjorngaard, J.H., Asvold, B.O., Gabrielsen, M.E., Campbell, A., Marioni, R.E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T.S., Wannamethee, S.G., Lahti, J., Räikkönen, K., Palotie, A., Wong, A., Dalgard, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K.O., Kuh, D, Eriksson, J.G., Whincup, P.H., Mbarek, H., de Geus, E.J.C., Vink, J.M., Boomsma, D.I., Davey Smith, G., Lawlor, D.A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J.W., Power, C., Hyppönen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimaki, M., Smith, B.H., Hayward, C., Sorensen, T.I.A., Thuesen, B.H., Sattar, N., Morris, R.W., Romundstad, P.R., Munafò, M., Jarvelin, M.R., Husemoen, L.L.N.
Veröffentlicht in: Linneberg , A , Jacobsen , R K , Skaaby , T , Taylor , A E , Fluharty , M E , Jeppesen , J , Bjorngaard , J H , Asvold , B O , Gabrielsen , M E , Campbell , A , Marioni , R E , Kumari , M , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Ahluwalia , T S , Wannamethee , S G , Lahti , J , Räikkönen , K , Palotie , A , Wong , A , Dalgard , C , Ford , I , Ben-Shlomo , Y , Christiansen , L , Kyvik , K O , Kuh , D , Eriksson , J G , Whincup , P H , Mbarek , H , de Geus , E J C , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D A , Kisialiou , A , McConnachie , A , Padmanabhan , S , Jukema , J W , Power , C , Hyppönen , E , Preisig , M , Waeber , G , Vollenweider , P , Korhonen , T , Laatikainen , T , Salomaa , V , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Sorensen , T I A , Thuesen , B H , Sattar , N , Morris , R W , Romundstad , P R , Munafò , M , Jarvelin , M R & Husemoen , L L N 2015 , ' Effect of Smoking on Blood Pressure and Resting Heart Rate - A Mendelian Randomization Meta-Analysis in the CARTA Consortium ' , Circulation: Cardiovascular genetics , vol. 8 , no. 6 , pp. 832-841 . https://doi.org/10.1161/CIRCGENETICS.115.001225;
2015
Veröffentlicht in: Linneberg , A , Jacobsen , R K , Skaaby , T , Taylor , A E , Fluharty , M E , Jeppesen , J , Bjorngaard , J H , Asvold , B O , Gabrielsen , M E , Campbell , A , Marioni , R E , Kumari , M , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Ahluwalia , T S , Wannamethee , S G , Lahti , J , Räikkönen , K , Palotie , A , Wong , A , Dalgard , C , Ford , I , Ben-Shlomo , Y , Christiansen , L , Kyvik , K O , Kuh , D , Eriksson , J G , Whincup , P H , Mbarek , H , de Geus , E J C , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D A , Kisialiou , A , McConnachie , A , Padmanabhan , S , Jukema , J W , Power , C , Hyppönen , E , Preisig , M , Waeber , G , Vollenweider , P , Korhonen , T , Laatikainen , T , Salomaa , V , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Sorensen , T I A , Thuesen , B H , Sattar , N , Morris , R W , Romundstad , P R , Munafò , M , Jarvelin , M R & Husemoen , L L N 2015 , ' Effect of Smoking on Blood Pressure and Resting Heart Rate - A Mendelian Randomization Meta-Analysis in the CARTA Consortium ' , Circulation: Cardiovascular genetics , vol. 8 , no. 6 , pp. 832-841 . https://doi.org/10.1161/CIRCGENETICS.115.001225;
2015
4
Taylor, A.E., Morris, R.W., Fluharty, M.E., Bjorngaard, J.H., Asvold, B.O., Gabrielsen, M.E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L.L.N., Skaaby, T., Ahluwalia, T.S., Treur, J.L., Willemsen, G., Dale, C., Wannamethee, S.G., Lahti, J., Palotie, A., Räikkönen, K., Kisialiou, A., McConnachie, A., Padmanabhan, S., Wong, A., Dalgard, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, L.J., Fergusson, D., Kennedy, M.A., Frayling, T.M., Nohr, E.A., Christiansen, L., Ohm Kyvik, K., Kuh, D, Watt, G., Eriksson, J., Whincup, P.H., Vink, J.M., Boomsma, D.I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J.W., Power, C., Hyppönen, E., Järvelin, M.R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B.H., Hayward, C., Romundstad, P.R., Sørensen, T.I.A., Munafo, M.R., Sattar, N.
Veröffentlicht in: Taylor , A E , Morris , R W , Fluharty , M E , Bjorngaard , J H , Asvold , B O , Gabrielsen , M E , Campbell , A , Marioni , R , Kumari , M , Hällfors , J , Männistö , S , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Husemoen , L L N , Skaaby , T , Ahluwalia , T S , Treur , J L , Willemsen , G , Dale , C , Wannamethee , S G , Lahti , J , Palotie , A , Räikkönen , K , Kisialiou , A , McConnachie , A , Padmanabhan , S , Wong , A , Dalgard , C , Paternoster , L , Ben-Shlomo , Y , Tyrrell , J , Horwood , L J , Fergusson , D , Kennedy , M A , Frayling , T M , Nohr , E A , Christiansen , L , Ohm Kyvik , K , Kuh , D , Watt , G , Eriksson , J , Whincup , P H , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D , Linneberg , A , Ford , I , Jukema , J W , Power , C , Hyppönen , E , Järvelin , M R , Preisig , M , Borodulin , K , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Romundstad , P R , Sørensen , T I A , Munafo , M R & Sattar , N 2014 , ' Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers ' , PLoS Genetics , vol. 10 , no. 12 , e1004799 . https://doi.org/10.1371/journal.pgen.1004799;
2014
Veröffentlicht in: Taylor , A E , Morris , R W , Fluharty , M E , Bjorngaard , J H , Asvold , B O , Gabrielsen , M E , Campbell , A , Marioni , R , Kumari , M , Hällfors , J , Männistö , S , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Husemoen , L L N , Skaaby , T , Ahluwalia , T S , Treur , J L , Willemsen , G , Dale , C , Wannamethee , S G , Lahti , J , Palotie , A , Räikkönen , K , Kisialiou , A , McConnachie , A , Padmanabhan , S , Wong , A , Dalgard , C , Paternoster , L , Ben-Shlomo , Y , Tyrrell , J , Horwood , L J , Fergusson , D , Kennedy , M A , Frayling , T M , Nohr , E A , Christiansen , L , Ohm Kyvik , K , Kuh , D , Watt , G , Eriksson , J , Whincup , P H , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D , Linneberg , A , Ford , I , Jukema , J W , Power , C , Hyppönen , E , Järvelin , M R , Preisig , M , Borodulin , K , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Romundstad , P R , Sørensen , T I A , Munafo , M R & Sattar , N 2014 , ' Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers ' , PLoS Genetics , vol. 10 , no. 12 , e1004799 . https://doi.org/10.1371/journal.pgen.1004799;
2014
5
van Leeuwen, E., Karssen, L., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., Kanterakis, A., Trompet, S., Postmus, I., Verweij, N., van Enckevort, D., Huffman, J., White, C., Feitosa, M., Bartz, T., Manichaikul, A., Joshi, P., Peloso, G., Deelen, P., van Dijk, F., Willemsen, G., de Geus, E., Milaneschi, Y., Penninx, B., Francioli, L., Menelaou, A., Pulit, S., Rivadeneira, F., Hofman, A., Oostra, B., Franco, O., Leach, I., Beekman, M., de Craen, A., Uh, H., Trochet, H., Hocking, L., Porteous, D., Sattar, N., Packard, C., Buckley, B., Brody, J., Bis, J., Rotter, J., Mychaleckyj, J., Campbell, H., Duan, Q., Lange, L., Wilson, J., Hayward, C., Polasek, O., Vitart, V., Rudan, I., Wright, A., Rich, S., Psaty, B., Borecki, I., Kearney, P., Stott, D., Cupples, L., including authors, Stoneking, M., Li, M., & others, Jukema, J., van der Harst, P., Sijbrands, E., Hottenga, J., Uitterlinden, A., Swertz, M., van Ommen, G., de Bakker, P., Slagboom, P., Boomsma, D., Wijmenga, C., van Duijn, C.
2015
2015
6
Deelen, J., Beekman, M., Uh, H.W., Broer, L., Ayers, K.L., Tan, Q., Kamatani, Y., Bennet, A.M., Tamm, R., Trompet, S., Gudbjartsson, D.F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H.J., Crocco, P., van den Akker, E.B., Böhringer, S., Helmer, Q., Nelson, C.P., Saunders, G.I., Alver, M., Andersen-Ranberg, K., Breen, M.E., van der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J.C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E.J.C., Harrow, J., van Heemst, D., Heijmans, B.T., Heinsen, F.A., Hottenga, J.J., Hofman, A., Jeune, B., Jonsson, P.V., Lathrop, M., Lechner, D., Martin-Ruiz, C., McNerlan, S.E., Mihailov, E., Montesanto, A., Mooijaart, S.P., Murphy, A., Nohr, E.A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O.A., Salvioli, S., Sattar, N., Schreiber, S, Stefansson, H., Stott, D.J., Tiemeier, H., Uitterlinden, A.G., Westendorp, R.G.J., Willemsen, G., Samani, N.J., Galan, P., Sørensen, T.I.A., Boomsma, D.I., Jukema, J.W., Maeve Rea, I., Passarino, G., de Craen, A.J., Christensen, K., Nebel, A., Stefansson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T.B.L., van Duijn, C.M., Franceschi, C., Houwing-Duistermaat, J.J., Slagboom, P.E.
Veröffentlicht in: Deelen , J , Beekman , M , Uh , H W , Broer , L , Ayers , K L , Tan , Q , Kamatani , Y , Bennet , A M , Tamm , R , Trompet , S , Gudbjartsson , D F , Flachsbart , F , Rose , G , Viktorin , A , Fischer , K , Nygaard , M , Cordell , H J , Crocco , P , van den Akker , E B , Böhringer , S , Helmer , Q , Nelson , C P , Saunders , G I , Alver , M , Andersen-Ranberg , K , Breen , M E , van der Breggen , R , Caliebe , A , Capri , M , Cevenini , E , Collerton , J C , Dato , S , Davies , K , Ford , I , Gampe , J , Garagnani , P , de Geus , E J C , Harrow , J , van Heemst , D , Heijmans , B T , Heinsen , F A , Hottenga , J J , Hofman , A , Jeune , B , Jonsson , P V , Lathrop , M , Lechner , D , Martin-Ruiz , C , McNerlan , S E , Mihailov , E , Montesanto , A , Mooijaart , S P , Murphy , A , Nohr , E A , Paternoster , L , Postmus , I , Rivadeneira , F , Ross , O A , Salvioli , S , Sattar , N , Schreiber , S , Stefansson , H , Stott , D J , Tiemeier , H , Uitterlinden , A G , Westendorp , R G J , Willemsen , G , Samani , N J , Galan , P , Sørensen , T I A , Boomsma , D I , Jukema , J W , Maeve Rea , I , Passarino , G , de Craen , A J , Christensen , K , Nebel , A , Stefansson , K , Metspalu , A , Magnusson , P , Blanché , H , Christiansen , L , Kirkwood , T B L , van Duijn , C M , Franceschi , C , Houwing-Duistermaat , J J & Slagboom , P E 2014 , ' Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age ' , Human Molecular Genetics , vol. 23 , no. 16 , pp. 4420-4432 . https://doi.org/10.1093/hmg/ddu139;
2014
Veröffentlicht in: Deelen , J , Beekman , M , Uh , H W , Broer , L , Ayers , K L , Tan , Q , Kamatani , Y , Bennet , A M , Tamm , R , Trompet , S , Gudbjartsson , D F , Flachsbart , F , Rose , G , Viktorin , A , Fischer , K , Nygaard , M , Cordell , H J , Crocco , P , van den Akker , E B , Böhringer , S , Helmer , Q , Nelson , C P , Saunders , G I , Alver , M , Andersen-Ranberg , K , Breen , M E , van der Breggen , R , Caliebe , A , Capri , M , Cevenini , E , Collerton , J C , Dato , S , Davies , K , Ford , I , Gampe , J , Garagnani , P , de Geus , E J C , Harrow , J , van Heemst , D , Heijmans , B T , Heinsen , F A , Hottenga , J J , Hofman , A , Jeune , B , Jonsson , P V , Lathrop , M , Lechner , D , Martin-Ruiz , C , McNerlan , S E , Mihailov , E , Montesanto , A , Mooijaart , S P , Murphy , A , Nohr , E A , Paternoster , L , Postmus , I , Rivadeneira , F , Ross , O A , Salvioli , S , Sattar , N , Schreiber , S , Stefansson , H , Stott , D J , Tiemeier , H , Uitterlinden , A G , Westendorp , R G J , Willemsen , G , Samani , N J , Galan , P , Sørensen , T I A , Boomsma , D I , Jukema , J W , Maeve Rea , I , Passarino , G , de Craen , A J , Christensen , K , Nebel , A , Stefansson , K , Metspalu , A , Magnusson , P , Blanché , H , Christiansen , L , Kirkwood , T B L , van Duijn , C M , Franceschi , C , Houwing-Duistermaat , J J & Slagboom , P E 2014 , ' Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age ' , Human Molecular Genetics , vol. 23 , no. 16 , pp. 4420-4432 . https://doi.org/10.1093/hmg/ddu139;
2014