1
Simonis-Bik, A.M.C., Boomsma, D.I., Dekker, J.M., Diamant, M., de Geus, E.J.C., Hart, L.M., Heine, R.J., Kramer, M.H.H., Maassen, J.A., Mari, A., Tura, A., Willemsen, G., Eekhoff, E.M.W.
Veröffentlicht in: Simonis-Bik , A M C , Boomsma , D I , Dekker , J M , Diamant , M , de Geus , E J C , Hart , L M , Heine , R J , Kramer , M H H , Maassen , J A , Mari , A , Tura , A , Willemsen , G & Eekhoff , E M W 2011 , ' The heritability of beta cell function parameters in a mixed meal test design ' , Diabetologia , vol. 54 , no. 5 , pp. 1043-1051 . https://doi.org/10.1007/s00125-011-2060-5;
2011
Veröffentlicht in: Simonis-Bik , A M C , Boomsma , D I , Dekker , J M , Diamant , M , de Geus , E J C , Hart , L M , Heine , R J , Kramer , M H H , Maassen , J A , Mari , A , Tura , A , Willemsen , G & Eekhoff , E M W 2011 , ' The heritability of beta cell function parameters in a mixed meal test design ' , Diabetologia , vol. 54 , no. 5 , pp. 1043-1051 . https://doi.org/10.1007/s00125-011-2060-5;
2011
2
Timmermans, Erik J., Lakerveld, Jeroen, Beulens, Joline W.J., Boomsma, Dorret I., Kramer, Sophia E., Oosterman, Mirjam, Willemsen, Gonneke, Stam, Mariska, Nijpels, Giel, Schuengel, Carlo, Smit, Jan H., Brunekreef, Bert, Dekkers, Jasper E.C., Deeg, Dorly J.H., Penninx, Brenda W.J.H., Huisman, Martijn
Veröffentlicht in: Timmermans , E J , Lakerveld , J , Beulens , J W J , Boomsma , D I , Kramer , S E , Oosterman , M , Willemsen , G , Stam , M , Nijpels , G , Schuengel , C , Smit , J H , Brunekreef , B , Dekkers , J E C , Deeg , D J H , Penninx , B W J H & Huisman , M 2018 , ' Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands ' , BMJ Open , vol. 8 , no. 6 , e021597 , pp. 1-14 . https://doi.org/10.1136/bmjopen-2018-021597;
2018
Veröffentlicht in: Timmermans , E J , Lakerveld , J , Beulens , J W J , Boomsma , D I , Kramer , S E , Oosterman , M , Willemsen , G , Stam , M , Nijpels , G , Schuengel , C , Smit , J H , Brunekreef , B , Dekkers , J E C , Deeg , D J H , Penninx , B W J H & Huisman , M 2018 , ' Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands ' , BMJ Open , vol. 8 , no. 6 , e021597 , pp. 1-14 . https://doi.org/10.1136/bmjopen-2018-021597;
2018
3
Generaal, Ellen, Hoogendijk, Emiel O., Stam, Mariska, Henke, Celina E., Rutters, Femke, Oosterman, Mirjam, Huisman, Martijn, Kramer, Sophia E., Elders, Petra J.M., Timmermans, Erik J., Lakerveld, Jeroen, Koomen, Eric, Ten Have, Margreet, De Graaf, Ron, Snijder, Marieke B., Stronks, Karien, Willemsen, Gonneke, Boomsma, Dorret I., Smit, Johannes H., Penninx, Brenda W.J.H.
Veröffentlicht in: Generaal , E , Hoogendijk , E O , Stam , M , Henke , C E , Rutters , F , Oosterman , M , Huisman , M , Kramer , S E , Elders , P J M , Timmermans , E J , Lakerveld , J , Koomen , E , Ten Have , M , De Graaf , R , Snijder , M B , Stronks , K , Willemsen , G , Boomsma , D I , Smit , J H & Penninx , B W J H 2019 , ' Neighbourhood characteristics and prevalence and severity of depression : pooled analysis of eight Dutch cohort studies ' , The British journal of psychiatry : the journal of mental science , vol. 215 , no. 2 , pp. 468-475 . https://doi.org/10.1192/bjp.2019.100;
2019
Veröffentlicht in: Generaal , E , Hoogendijk , E O , Stam , M , Henke , C E , Rutters , F , Oosterman , M , Huisman , M , Kramer , S E , Elders , P J M , Timmermans , E J , Lakerveld , J , Koomen , E , Ten Have , M , De Graaf , R , Snijder , M B , Stronks , K , Willemsen , G , Boomsma , D I , Smit , J H & Penninx , B W J H 2019 , ' Neighbourhood characteristics and prevalence and severity of depression : pooled analysis of eight Dutch cohort studies ' , The British journal of psychiatry : the journal of mental science , vol. 215 , no. 2 , pp. 468-475 . https://doi.org/10.1192/bjp.2019.100;
2019
4
Bik-Simonis, A.M.C., Nijpels, M.G.A.A.M., van Haeften, T., Houwing-Duistermaat, J.J., Boomsma, D.I., Reiling, E., van Hove, E.C., Diamant, M., Kramer, M.H.H., Heine, R.J., Maassen, J.A., Slagboom, P.E., Willemsen, G., Dekker, J.M., Eekhoff, E.M.W., de Geus, E.J.C., Hart, L.M.
Veröffentlicht in: Bik-Simonis , A M C , Nijpels , M G A A M , van Haeften , T , Houwing-Duistermaat , J J , Boomsma , D I , Reiling , E , van Hove , E C , Diamant , M , Kramer , M H H , Heine , R J , Maassen , J A , Slagboom , P E , Willemsen , G , Dekker , J M , Eekhoff , E M W , de Geus , E J C & Hart , L M 2010 , ' Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A and MTNR1B affect different aspects of pancreatic beta cell function ' , Diabetes , vol. 59 , no. 1 , pp. 293-301 . https://doi.org/10.2337/db09-1048;
2010
Veröffentlicht in: Bik-Simonis , A M C , Nijpels , M G A A M , van Haeften , T , Houwing-Duistermaat , J J , Boomsma , D I , Reiling , E , van Hove , E C , Diamant , M , Kramer , M H H , Heine , R J , Maassen , J A , Slagboom , P E , Willemsen , G , Dekker , J M , Eekhoff , E M W , de Geus , E J C & Hart , L M 2010 , ' Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A and MTNR1B affect different aspects of pancreatic beta cell function ' , Diabetes , vol. 59 , no. 1 , pp. 293-301 . https://doi.org/10.2337/db09-1048;
2010
5
Hart, L.M., Bik-Simonis, A.M.C., Nijpels, G., van Haeften, T.W., Schäfer, S.A., Houwing-Duistermaat, J.J., Boomsma, D.I., Groenewoud, M.J., Reiling, E., van Hove, E.C., Diamant, M., Kramer, M.H.H., Heine, R.J., Maassen, J.A., Kirchhoff, K., Machicao, F., Häring, H.U., Slagboom, P.E., Willemsen, G., Eekhoff, E.M.W., de Geus, E.J.C., Dekker, J.J.M., Fritsche, A.
Veröffentlicht in: Hart , L M , Bik-Simonis , A M C , Nijpels , G , van Haeften , T W , Schäfer , S A , Houwing-Duistermaat , J J , Boomsma , D I , Groenewoud , M J , Reiling , E , van Hove , E C , Diamant , M , Kramer , M H H , Heine , R J , Maassen , J A , Kirchhoff , K , Machicao , F , Häring , H U , Slagboom , P E , Willemsen , G , Eekhoff , E M W , de Geus , E J C , Dekker , J J M & Fritsche , A 2010 , ' Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First Phase Glucose Stimulated Insulin Secretion During Hyperglycemic Clamps ' , Diabetes , vol. 59 , no. 1 , pp. 287-292 . https://doi.org/10.2337/db09-0736;
2010
Veröffentlicht in: Hart , L M , Bik-Simonis , A M C , Nijpels , G , van Haeften , T W , Schäfer , S A , Houwing-Duistermaat , J J , Boomsma , D I , Groenewoud , M J , Reiling , E , van Hove , E C , Diamant , M , Kramer , M H H , Heine , R J , Maassen , J A , Kirchhoff , K , Machicao , F , Häring , H U , Slagboom , P E , Willemsen , G , Eekhoff , E M W , de Geus , E J C , Dekker , J J M & Fritsche , A 2010 , ' Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First Phase Glucose Stimulated Insulin Secretion During Hyperglycemic Clamps ' , Diabetes , vol. 59 , no. 1 , pp. 287-292 . https://doi.org/10.2337/db09-0736;
2010
6
Gudmundsdottir, Valborg, Pedersen, Helle Krogh, Allebrandt, Karla Viviani, Brorsson, Caroline, van Leeuwen, Nienke, Banasik, Karina, Mahajan, Anubha, Groves, Christopher J, van de Bunt, Martijn, Dawed, Adem Y, Fritsche, Andreas, Staiger, Harald, Simonis-Bik, Annemarie M C, Deelen, Joris, Kramer, Mark H H, Dietrich, Axel, Hübschle, Thomas, Willemsen, Gonneke, Häring, Hans-Ulrich, de Geus, Eco J C, Boomsma, Dorret I, Eekhoff, Elisabeth M W, Ferrer, Jorge, McCarthy, Mark I, Pearson, Ewan R, Gupta, Ramneek, Brunak, Søren, 't Hart, Leen M
Veröffentlicht in: Gudmundsdottir , V , Pedersen , H K , Allebrandt , K V , Brorsson , C , van Leeuwen , N , Banasik , K , Mahajan , A , Groves , C J , van de Bunt , M , Dawed , A Y , Fritsche , A , Staiger , H , Simonis-Bik , A M C , Deelen , J , Kramer , M H H , Dietrich , A , Hübschle , T , Willemsen , G , Häring , H-U , de Geus , E J C , Boomsma , D I , Eekhoff , E M W , Ferrer , J , McCarthy , M I , Pearson , E R , Gupta , R , Brunak , S & 't Hart , L M 2018 , ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ' , PLoS ONE , vol. 13 , no. 1 , e0189886 , pp. e0189886 . https://doi.org/10.1371/journal.pone.0189886;
2018
Veröffentlicht in: Gudmundsdottir , V , Pedersen , H K , Allebrandt , K V , Brorsson , C , van Leeuwen , N , Banasik , K , Mahajan , A , Groves , C J , van de Bunt , M , Dawed , A Y , Fritsche , A , Staiger , H , Simonis-Bik , A M C , Deelen , J , Kramer , M H H , Dietrich , A , Hübschle , T , Willemsen , G , Häring , H-U , de Geus , E J C , Boomsma , D I , Eekhoff , E M W , Ferrer , J , McCarthy , M I , Pearson , E R , Gupta , R , Brunak , S & 't Hart , L M 2018 , ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ' , PLoS ONE , vol. 13 , no. 1 , e0189886 , pp. e0189886 . https://doi.org/10.1371/journal.pone.0189886;
2018
7
't Hart, L.M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L.A., Dekker, J.M., Alssema, M.J., Fadista, J., Carlotti, F., Gjesing, A.P., Palmer, C.N.A., van Haeften, T.W., Herzberg-Schäfer, S.A., Bik-Simonis, A.M.C., Houwing-Duistermaat, J.J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F., Willemsen, G., Heine, R.J., Kramer, M.H.H., Holst, J.J., de Koning, E.J.P., Häring, H.U., Pedersen, O., Groop, L., de Geus, E.J.C., Slagboom, P.E., Boomsma, D.I., Eekhoff, E.M.W., Pearson, E.R., Diamant, M.
Veröffentlicht in: 't Hart , L M , Fritsche , A , Nijpels , G , van Leeuwen , N , Donnelly , L A , Dekker , J M , Alssema , M J , Fadista , J , Carlotti , F , Gjesing , A P , Palmer , C N A , van Haeften , T W , Herzberg-Schäfer , S A , Bik-Simonis , A M C , Houwing-Duistermaat , J J , Helmer , Q , Deelen , J , Guigas , B , Hansen , T , Machicao , F , Willemsen , G , Heine , R J , Kramer , M H H , Holst , J J , de Koning , E J P , Häring , H U , Pedersen , O , Groop , L , de Geus , E J C , Slagboom , P E , Boomsma , D I , Eekhoff , E M W , Pearson , E R & Diamant , M 2013 , ' The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway ' , Diabetes , vol. 62 , no. 9 , pp. 3275-3281 . https://doi.org/10.2337/db13-0227;
2013
Veröffentlicht in: 't Hart , L M , Fritsche , A , Nijpels , G , van Leeuwen , N , Donnelly , L A , Dekker , J M , Alssema , M J , Fadista , J , Carlotti , F , Gjesing , A P , Palmer , C N A , van Haeften , T W , Herzberg-Schäfer , S A , Bik-Simonis , A M C , Houwing-Duistermaat , J J , Helmer , Q , Deelen , J , Guigas , B , Hansen , T , Machicao , F , Willemsen , G , Heine , R J , Kramer , M H H , Holst , J J , de Koning , E J P , Häring , H U , Pedersen , O , Groop , L , de Geus , E J C , Slagboom , P E , Boomsma , D I , Eekhoff , E M W , Pearson , E R & Diamant , M 2013 , ' The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway ' , Diabetes , vol. 62 , no. 9 , pp. 3275-3281 . https://doi.org/10.2337/db13-0227;
2013
8
van Vliet-Ostaptchouk, J.V., van Haeften, T.W., Landman, G.W.D., Reiling, E., Kleefstra, N., Bilo, H.J.G., Klungel, O.H., de Boer, A., van Diemen, C.C., Wijmenga, C., Boezen, H.M., Dekker, J.M., van 't Riet, E., Nijpels, G., Welschen, L.M.C., Zavrelová, H., Bruin, E.J., Elbers, C.C., Bauer, F., Onland-Moret, N.C., van der Schouw, Y.T., Grobbee, D.E., Spijkerman, A.M.W., van der Aa, D.L., Bik-Simonis, A.M.C., Eekhoff, E.M.W., Diamant, M., Kramer, M.H.H., Boomsma, D.I., de Geus, E.J.C., Willemsen, G., Slagboom, P.E., Hofker, M.H., Hart, L.M.
Veröffentlicht in: van Vliet-Ostaptchouk , J V , van Haeften , T W , Landman , G W D , Reiling , E , Kleefstra , N , Bilo , H J G , Klungel , O H , de Boer , A , van Diemen , C C , Wijmenga , C , Boezen , H M , Dekker , J M , van 't Riet , E , Nijpels , G , Welschen , L M C , Zavrelová , H , Bruin , E J , Elbers , C C , Bauer , F , Onland-Moret , N C , van der Schouw , Y T , Grobbee , D E , Spijkerman , A M W , van der Aa , D L , Bik-Simonis , A M C , Eekhoff , E M W , Diamant , M , Kramer , M H H , Boomsma , D I , de Geus , E J C , Willemsen , G , Slagboom , P E , Hofker , M H & Hart , L M 2012 , ' Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp ' , PLoS ONE , vol. 7 , no. 3 , e32148 . https://doi.org/10.1371/journal.pone.0032148;
2012
Veröffentlicht in: van Vliet-Ostaptchouk , J V , van Haeften , T W , Landman , G W D , Reiling , E , Kleefstra , N , Bilo , H J G , Klungel , O H , de Boer , A , van Diemen , C C , Wijmenga , C , Boezen , H M , Dekker , J M , van 't Riet , E , Nijpels , G , Welschen , L M C , Zavrelová , H , Bruin , E J , Elbers , C C , Bauer , F , Onland-Moret , N C , van der Schouw , Y T , Grobbee , D E , Spijkerman , A M W , van der Aa , D L , Bik-Simonis , A M C , Eekhoff , E M W , Diamant , M , Kramer , M H H , Boomsma , D I , de Geus , E J C , Willemsen , G , Slagboom , P E , Hofker , M H & Hart , L M 2012 , ' Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp ' , PLoS ONE , vol. 7 , no. 3 , e32148 . https://doi.org/10.1371/journal.pone.0032148;
2012
9
Molnos, Sophie, Wahl, Simone, Haid, Mark, Eekhoff, E Marelise W, Pool, René, Floegel, Anna, Deelen, Joris, Much, Daniela, Prehn, Cornelia, Breier, Michaela, Draisma, Harmen H, van Leeuwen, Nienke, Simonis-Bik, Annemarie M C, Jonsson, Anna, Willemsen, Gonneke, Bernigau, Wolfgang, Wang-Sattler, Rui, Suhre, Karsten, Peters, Annette, Thorand, Barbara, Herder, Christian, Rathmann, Wolfgang, Roden, Michael, Gieger, Christian, Kramer, Mark H H, van Heemst, Diana, Pedersen, Helle K, Gudmundsdottir, Valborg, Schulze, Matthias B, Pischon, Tobias, de Geus, Eco J C, Boeing, Heiner, Boomsma, Dorret I, Ziegler, Anette G, Slagboom, P. Eline, Hummel, Sandra, Beekman, Marian, Grallert, Harald, Brunak, Søren, McCarthy, Mark I, Gupta, Ramneek, Pearson, Ewan R, Adamski, Jerzy, 't Hart, Leen M
Veröffentlicht in: Molnos , S , Wahl , S , Haid , M , Eekhoff , E M W , Pool , R , Floegel , A , Deelen , J , Much , D , Prehn , C , Breier , M , Draisma , H H , van Leeuwen , N , Simonis-Bik , A M C , Jonsson , A , Willemsen , G , Bernigau , W , Wang-Sattler , R , Suhre , K , Peters , A , Thorand , B , Herder , C , Rathmann , W , Roden , M , Gieger , C , Kramer , M H H , van Heemst , D , Pedersen , H K , Gudmundsdottir , V , Schulze , M B , Pischon , T , de Geus , E J C , Boeing , H , Boomsma , D I , Ziegler , A G , Slagboom , P E , Hummel , S , Beekman , M , Grallert , H , Brunak , S , McCarthy , M I , Gupta , R , Pearson , E R , Adamski , J & 't Hart , L M 2018 , ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ' , Diabetologia , vol. 61 , no. 1 , pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7;
2018
Veröffentlicht in: Molnos , S , Wahl , S , Haid , M , Eekhoff , E M W , Pool , R , Floegel , A , Deelen , J , Much , D , Prehn , C , Breier , M , Draisma , H H , van Leeuwen , N , Simonis-Bik , A M C , Jonsson , A , Willemsen , G , Bernigau , W , Wang-Sattler , R , Suhre , K , Peters , A , Thorand , B , Herder , C , Rathmann , W , Roden , M , Gieger , C , Kramer , M H H , van Heemst , D , Pedersen , H K , Gudmundsdottir , V , Schulze , M B , Pischon , T , de Geus , E J C , Boeing , H , Boomsma , D I , Ziegler , A G , Slagboom , P E , Hummel , S , Beekman , M , Grallert , H , Brunak , S , McCarthy , M I , Gupta , R , Pearson , E R , Adamski , J & 't Hart , L M 2018 , ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ' , Diabetologia , vol. 61 , no. 1 , pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7;
2018
10
Wood, Andrew R, Jonsson, Anna, Jackson, Anne U, Wang, Nan, van Leewen, Nienke, Palmer, Nicholette D, Kobes, Sayuko, Deelen, Joris, Boquete-Vilarino, Lorena, Paananen, Jussi, Stančáková, Alena, Boomsma, Dorret I, de Geus, J.C.N., Eekhoff, Elisabeth Mw, Fritsche, Andreas, Kramer, Mark H H, Nijpels, Giel, Simonis-Bik, A.M.C., van Haeften, Timon W, Mahajan, Anubha, Boehnke, Michael, Bergman, Richard N, Tuomilehto, Jaakko, Collins, Francis S, Mohlke, Karen L, Banasik, Karina, Groves, Christopher J, McCarthy, Mark I, Pearson, Ewan R, Natali, Andrea, Mari, Andrea, Buchanan, Thomas A, Taylor, Kent D, Xiang, Anny H, Gjesing, Anette P, Grarup, Niels, Eiberg, Hans, Pedersen, Oluf, Chen, Yii-Derr, Laakso, Markku, Norris, Jill M, Smith, Ulf, Wagenknecht, Lynne E, Baier, Leslie, Bowden, Donald W, Hansen, Torben, Walker, Mark, Watanabe, Richard M, 't Hart, Leen M, Hanson, Robert L, Frayling, Timothy M
Veröffentlicht in: Wood , A R , Jonsson , A , Jackson , A U , Wang , N , van Leewen , N , Palmer , N D , Kobes , S , Deelen , J , Boquete-Vilarino , L , Paananen , J , Stančáková , A , Boomsma , D I , de Geus , J C N , Eekhoff , E M , Fritsche , A , Kramer , M H H , Nijpels , G , Simonis-Bik , A M C , van Haeften , T W , Mahajan , A , Boehnke , M , Bergman , R N , Tuomilehto , J , Collins , F S , Mohlke , K L , Banasik , K , Groves , C J , McCarthy , M I , Pearson , E R , Natali , A , Mari , A , Buchanan , T A , Taylor , K D , Xiang , A H , Gjesing , A P , Grarup , N , Eiberg , H , Pedersen , O , Chen , Y-D , Laakso , M , Norris , J M , Smith , U , Wagenknecht , L E , Baier , L , Bowden , D W , Hansen , T , Walker , M , Watanabe , R M , 't Hart , L M , Hanson , R L & Frayling , T M 2017 , ' A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants ' , Diabetes , vol. 66 , no. 8 , pp. 2296-2309 . https://doi.org/10.2337/db16-1452;
2017
Veröffentlicht in: Wood , A R , Jonsson , A , Jackson , A U , Wang , N , van Leewen , N , Palmer , N D , Kobes , S , Deelen , J , Boquete-Vilarino , L , Paananen , J , Stančáková , A , Boomsma , D I , de Geus , J C N , Eekhoff , E M , Fritsche , A , Kramer , M H H , Nijpels , G , Simonis-Bik , A M C , van Haeften , T W , Mahajan , A , Boehnke , M , Bergman , R N , Tuomilehto , J , Collins , F S , Mohlke , K L , Banasik , K , Groves , C J , McCarthy , M I , Pearson , E R , Natali , A , Mari , A , Buchanan , T A , Taylor , K D , Xiang , A H , Gjesing , A P , Grarup , N , Eiberg , H , Pedersen , O , Chen , Y-D , Laakso , M , Norris , J M , Smith , U , Wagenknecht , L E , Baier , L , Bowden , D W , Hansen , T , Walker , M , Watanabe , R M , 't Hart , L M , Hanson , R L & Frayling , T M 2017 , ' A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants ' , Diabetes , vol. 66 , no. 8 , pp. 2296-2309 . https://doi.org/10.2337/db16-1452;
2017