Childhood Takayasu arteritis: disease course and response to therapy

Individual risk factors for disease progression and flares in childhood TAK are unknown. [...]the aims of the study were: 1) to describe the presenting clinical, laboratory and angiographic features of childhood TAK patients, 2) to explore and compare efficacy and safety of childhood TAK treatment regimens and 3) to attempt to identify risk factors for adverse patient outcome in childhood TAK. Clearly, further studies including multicenter collaborations are needed to prospectively evaluate the potential benefit of biologic agents in childhood TAK. [...]more evidence is available, our data and... Mehr ...