The relationship between major depressive disorder (MDD) and bipolar disorder (BD) remains controversial. Previous research has reported differences and similarities in risk factors for MDD and BD, such as predisposing personality traits. For example, high neuroticism is related to both disorders, whereas openness to experience is specific for BD. This study examined the genetic association between personality and MDD and BD by applying polygenic scores for neuroticism, extraversion, openness to experience, agreeableness and conscientiousness to both disorders. Polygenic scores reflect the wei... Mehr ...
| Verfasser: |
Middeldorp, C.M.
de Moor, M.H.M.
McGrath, L.M.
Gordon, S.D.
Blackwood, D.H.
Costa, P.T.
Terracciano, A.
Krueger, R.F.
de Geus, E.J.C.
Nyholt, DR
Tanaka, T.
Esko, T.
Madden, P.A.F.
Derringer, J.
Amin, N.
Willemsen, G.
Hottenga, J.J.
Distel, M.A.
Uda, M.
Sanna, S.
Spinhoven, P.
Hartman, C.A.
Ripke, S.
Sullivan, P.F.
Realo, A.
Allik, J.
Heath, A.C.
Pergadia, M.L.
Agrawal, A.
Lin, P.
Grucza, R.A.
Widen, E.
Cousminer, D.L.
Eriksson, J.G.
Palotie, A.
Barnett, J.H.
Lee, P.H.
Luciano, M
Tenesa, A.
Davies, G.
Lopez, L.M.
Hansell, N.K.
Medland, S.E.
Ferrucci, L.
Schlessinger, D.
Montgomery, GW
Wright, M.J.
Aulchenko, Y.S.
Janssens, A.C.J.W.
Oostra, B.A.
Metspalu, A.
Abecasis, G.R.
Deary, I.J.
Räikkönen, K.
Bierut, L.J.
Martin, N.G.
Wray, N.R.
van Duijn, C.M.
Smoller, J.W.
Penninx, B.W.J.H.
Boomsma, D.I. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2011 |
| Reihe/Periodikum: |
Middeldorp , C M , de Moor , M H M , McGrath , L M , Gordon , S D , Blackwood , D H , Costa , P T , Terracciano , A , Krueger , R F , de Geus , E J C , Nyholt , DR , Tanaka , T , Esko , T , Madden , P A F , Derringer , J , Amin , N , Willemsen , G , Hottenga , J J , Distel , M A , Uda , M , Sanna , S , Spinhoven , P , Hartman , C A , Ripke , S , Sullivan , P F , Realo , A , Allik , J , Heath , A C , Pergadia , M L , Agrawal , A , Lin , P , Grucza , R A , Widen , E , Cousminer , D L , Eriksson , J G , Palotie , A , Barnett , J H , Lee , P H , Luciano , M , Tenesa , A , Davies , G , Lopez , L M , Hansell , N K , Medland , S E , Ferrucci , L , Schlessinger , D , Montgomery , GW , Wright , M J , Aulchenko , Y S , Janssens , A C J W , Oostra , B A , Metspalu , A , Abecasis , G R , Deary , I J , Räikkönen , K , Bierut , L J , Martin , N G , Wray , N R , van Duijn , C M , Smoller , J W , Penninx , B W J H & Boomsma , D I 2011 , ' The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data ' , Translational Psychiatry , vol. 1 , e50 . https://doi.org/10.1038/tp.2011.45 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-30455743 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/b6029679-049b-44db-af8c-37088bf2bbc8 |
