Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: in vivo therapeutic efficacy and kelch13 molecular marker surveillance ... : مراقبة مقاومة المتصورة المنجلية للأرتيميسينين في صباح، ماليزيا: الفعالية العلاجية في الجسم الحي ومراقبة العلامات الجزيئية للكلش 13 ...
Spreading Plasmodium falciparum artemisinin drug resistance threatens global malaria public health gains. Limited data exist to define the extent of P. falciparum artemisinin resistance southeast of the Greater Mekong region in Malaysia. A clinical efficacy study of oral artesunate (total target dose 12 mg/kg) daily for 3 days was conducted in patients with uncomplicated falciparum malaria and a parasite count < 100,000/µL admitted to 3 adjacent district hospitals in Sabah, East Malaysia. On day 3 and 4 all patients were administered split dose mefloquine (total dose 25 mg/kg) and followed... Mehr ...
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Dokumenttyp: | article-journal |
Erscheinungsdatum: | 2018 |
Verlag/Hrsg.: |
OpenAlex
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Schlagwörter: | Malaria / Public Health / Environmental and Occupational Health / Medicine / Health Sciences / Computational Methods in Drug Discovery / Computational Theory and Mathematics / Computer Science / Physical Sciences / Mechanisms of Drug-Induced Hepatotoxicity / Pharmacology / Toxicology and Pharmaceutics / Life Sciences / Artemisinin Resistance / Artemisinin / Artesunate / Plasmodium falciparum / Mefloquine / Parasitology / Drug resistance / Primaquine / Internal medicine / Veterinary medicine / Immunology / FOS: Clinical medicine / Biology / Chloroquine / Microbiology / FOS: Biological sciences / Pathology |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-29650031 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dx.doi.org/10.60692/s0y5s-nh918 |