Blood group chimerism in human multiple birth is not rare

Twin blood group chimerism seems to be very rare in humans. The 30–40 previously reported cases usually were found by mere coincidence during routine blood grouping in hospitals or blood banks. Usually in these cases frank blood group mixtures of, for example, 50/50%, 25/75%, or 5/95% at most were seen. Smaller percentages are very difficult to notice during routine work‐up. Using a sensitive fluorescence technique (sensitivity >0.01%) we detected blood group chimerism in 32/415 (8%) twin pairs and 12/57 (21%) triplet pairs, respectively, which is a higher incidence than reported previously... Mehr ...

Verfasser: van Dijk, B.A.
Boomsma, D.I.
de Man, A.J.M.
Dokumenttyp: Artikel
Erscheinungsdatum: 1996
Reihe/Periodikum: van Dijk , B A , Boomsma , D I & de Man , A J M 1996 , ' Blood group chimerism in human multiple birth is not rare ' , American Journal of Medical Genetics , vol. 61 , no. 3 , pp. 264-268 . https://doi.org/10.1002/(SICI)1096-8628(19960122)61:3<264::AID-AJMG11>3.0.CO;2-R
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29628416
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/54ca03f6-e966-4d7c-bd16-d39981485fb7

Twin blood group chimerism seems to be very rare in humans. The 30–40 previously reported cases usually were found by mere coincidence during routine blood grouping in hospitals or blood banks. Usually in these cases frank blood group mixtures of, for example, 50/50%, 25/75%, or 5/95% at most were seen. Smaller percentages are very difficult to notice during routine work‐up. Using a sensitive fluorescence technique (sensitivity >0.01%) we detected blood group chimerism in 32/415 (8%) twin pairs and 12/57 (21%) triplet pairs, respectively, which is a higher incidence than reported previously.