The netherlands is on track to meet the world health organization hepatitis C elimination targets by 2030

Background: The Netherlands strives for hepatitis C virus (HCV) elimination, in accordance with the World Health Organization targets. An accurate estimate when HCV elimination will be reached is elusive. We have embarked on a nationwide HCV elimination project (CELINE) that allowed us to harvest detailed data on the Dutch HCV epidemic. This study aims to provide a well‐supported timeline towards HCV elimination in The Netherlands. Methods: A previously published Markov model was used, adopting published data and unpublished CELINE project data. Two main scenarios were devised. In the Status Q... Mehr ...

Verfasser: Van Dijk, Marleen
Brakenhoff, Sylvia M.
Isfordink, Cas J.
Cheng, Wei‐Han
Blokzijl, Hans
Boland, Greet
Dofferhoff, Anthonius S.M.
Van Hoek, Bart
Van Nieuwkoop, Cees
Sonneveld, Milan J.
Van Der Valk, Marc
Drenth, Joost P.H.
De Knegt, Robert J.
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Van Dijk , M , Brakenhoff , S M , Isfordink , C J , Cheng , WH , Blokzijl , H , Boland , G , Dofferhoff , A S M , Van Hoek , B , Van Nieuwkoop , C , Sonneveld , M J , Van Der Valk , M , Drenth , J P H & De Knegt , R J 2021 , ' The netherlands is on track to meet the world health organization hepatitis C elimination targets by 2030 ' , Journal of Clinical Medicine , vol. 10 , no. 19 , 4562 . https://doi.org/10.3390/jcm10194562
Schlagwörter: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29626641
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://pure.eur.nl/en/publications/fd2e0a7b-fd93-4f95-9972-e998c79f9ba4

Background: The Netherlands strives for hepatitis C virus (HCV) elimination, in accordance with the World Health Organization targets. An accurate estimate when HCV elimination will be reached is elusive. We have embarked on a nationwide HCV elimination project (CELINE) that allowed us to harvest detailed data on the Dutch HCV epidemic. This study aims to provide a well‐supported timeline towards HCV elimination in The Netherlands. Methods: A previously published Markov model was used, adopting published data and unpublished CELINE project data. Two main scenarios were devised. In the Status Quo scenario, 2020 diagnosis and treatment levels remained constant in subsequent years. In the Gradual Decline scenario, an annual decrease of 10% in both diagnoses and treatments was implemented, starting in 2020. WHO incidence target was disregarded, due to low HCV incidence in The Netherlands (≤5 per 100,000). Results: Following the Status Quo and Gradual Decline scenarios, The Netherlands would meet WHO’s elimination targets by 2027 and 2032, respectively. From 2015 to 2030, liver‐related mortality would be reduced by 97% in the Status Quo and 93% in the Gradual Decline scenario. Compared to the Status Quo scenario, the Gradual Decline scenario would result in 12 excess cases of decompensated cirrhosis, 18 excess cases of hepatocellular carcinoma, and 20 excess cases of liverrelated death from 2020-2030. Conclusions: The Netherlands is on track to reach HCV elimination by 2030. However, it is vital that HCV elimination remains high on the agenda to ensure adequate numbers of patients are being diagnosed and treated.