The multitarget faecal immunochemical test for improving stool-based colorectal cancer screening programmes:a Dutch population-based, paired-design, intervention study

Background: The faecal immunochemical test (FIT) is widely employed for colorectal cancer screening. However, its sensitivity for advanced precursor lesions remains suboptimal. The multitarget FIT (mtFIT), measuring haemoglobin, calprotectin, and serpin family F member 2, has demonstrated enhanced sensitivity for advanced neoplasia, especially advanced adenomas, at equal specificity to FIT. This study aimed to prospectively validate and investigate the clinical utlitity of mtFIT versus FIT in a setting of population-based colorectal cancer screening. Methods: Individuals aged 55–75 years and w... Mehr ...

Verfasser: Wisse, Pieter H.A.
de Klaver, Willemijn
van Wifferen, Francine
van Maaren-Meijer, Frejanne G.
van Ingen, Huub E.
Meiqari, Lana
Huitink, Iris
Bierkens, Mariska
Lemmens, Margriet
Greuter, Marjolein J.E.
van Leerdam, Monique E.
Spaander, Manon C.W.
Dekker, Evelien
Coupé, Veerle M.H.
Carvalho, Beatriz
de Wit, Meike
Meijer, Gerrit A.
Dokumenttyp: Artikel
Erscheinungsdatum: 2024
Reihe/Periodikum: Wisse , P H A , de Klaver , W , van Wifferen , F , van Maaren-Meijer , F G , van Ingen , H E , Meiqari , L , Huitink , I , Bierkens , M , Lemmens , M , Greuter , M J E , van Leerdam , M E , Spaander , M C W , Dekker , E , Coupé , V M H , Carvalho , B , de Wit , M & Meijer , G A 2024 , ' The multitarget faecal immunochemical test for improving stool-based colorectal cancer screening programmes : a Dutch population-based, paired-design, intervention study ' , The Lancet Oncology , vol. 25 , no. 3 , pp. 326-337 . https://doi.org/10.1016/s1470-2045(23)00651-4
Schlagwörter: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29460093
Datenquelle: BASE; Originalkatalog
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Link(s) : https://pure.eur.nl/en/publications/8042e475-4874-4695-84b9-1ccb3c043ae8