External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort ...
Objective : To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods : Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that contained predictors commonly available were eligible for external validation. Results : 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion : O... Mehr ...
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| Dokumenttyp: | Dataset |
| Erscheinungsdatum: | 2019 |
| Verlag/Hrsg.: |
Taylor & Francis
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| Schlagwörter: | Cell Biology / Genetics / FOS: Biological sciences / Biotechnology / Immunology / FOS: Clinical medicine / 69999 Biological Sciences not elsewhere classified / 80699 Information Systems not elsewhere classified / FOS: Computer and information sciences / 19999 Mathematical Sciences not elsewhere classified / FOS: Mathematics / Cancer / Science Policy / Hematology |
| Sprache: | unknown |
| Permalink: | https://search.fid-benelux.de/Record/base-29399259 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://dx.doi.org/10.6084/m9.figshare.7871354 |
Objective : To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods : Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that contained predictors commonly available were eligible for external validation. Results : 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion : Only a few easily applicable prognostic models for all PE showed discrimination above 0.70, which is considered an acceptable performance. ...