peer reviewed ; To analyse the relationships between a psychological quality of life and employability skills among first-year students of social sciences at the universities of Luxembourg and Belgium. Method. 84 students initially registered at bachelor professional (Faculty LSHASE), and 91 at bachelor academic (Institut SHS Liege) completed questionnaires. Results Scores for psychological WHOQoL (74.3 vs 63.9 Liege) and environmental WHOQoL (73.3 vs 68.4) were better among the Luxembourg students, as was the score for employability skills (73.0 vs 68.3) than ISHS Belgium. Psychological WHOQoL score was correlated with perceived health, scores for social relationships and environmental WHOQol domains, and employability skills score (with the exceptions of the father’s professional status in Luxembourg and students age in Belgium). Effect between psychological WHOQoL and employability skills was only observed among Luxembourg students. Conclusion Good mental health is a key factor of possession of employability skills in Luxembourg where students are older and their studies are professional dies. ; F3R-INS-PUL-08SQLE > SQALES > > BAUMANN Michèle