Brugmansia Pers, belonging to the family Solanaceae, is a group commonly known as Floripondio, Angel’s Trumpets and Tree Datura, names associated with the use or manner of the plant. It has high alkaloid content, particularly Scopolamine, which is often used for induced intoxication for criminal purposes, when used in conjunction with central nervous system depressants in a mixture known as “burundanga”. Its flowers are large and colorful; its fruits are similar to those of cocoa. These plants are always found in clearings, orchards and gardens, since it is considered legal. At least eight species are naturally available, distributed in Central America and especially in South America, but records for Colombia are comparatively few and of low coverage, indicating the need for a national and continental review on the composition, distribution and variability of this genus. Despite Brugmansia being famous for its composition of alkaloids, Scopolamine is commercially extracted from other species. It is necessary to review the uses of this group of species, which in some cases range from ornamental, medicinal with external use, as well as their connotations in shamanistic rituals and witchcraft. The review should involve ethnobotanical aspects regarding genetic changes of populations associated with its use, the environments where it grows, its dispersion and associated biota, as well as the review from the medical, pharmacological, biogeographical, socio-legal perspective. ; Brugmansia Pers. es un grupo de Solanaceas conocido comúnmente como Borrachero, Floripondio, Cacao sabanero, Trompeta de ángel, denominaciones asociadas a los usos o a la forma de la planta. Tiene un alto contenido de alcaloides, en particular de Escopolamina, del cual es frecuente la intoxicación inducida con fines delictivos, cuando se utiliza en conjunto con depresores del sistema nervioso central en una mezcla conocida como “burundanga”. Sus flores son grandes y vistosas, sus frutos son similares por su forma a los del cacao, viven siempre ...