Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands

Abstract Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed during 2007–2020. We showed that 5‐year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel‐based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared... Mehr ...

Verfasser: van der Straten, Lina
Levin, Mark‐David
Visser, Otto
Posthuma, Eduardus F.M.
Doorduijn, Jeanette K.
Kater, Arnon P.
Dinmohamed, Avinash G.
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: eJHaem ; volume 3, issue 1, page 180-183 ; ISSN 2688-6146 2688-6146
Verlag/Hrsg.: Wiley
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29221644
Datenquelle: BASE; Originalkatalog
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Link(s) : http://dx.doi.org/10.1002/jha2.368

Abstract Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed during 2007–2020. We showed that 5‐year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel‐based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared to an age‐ and sex‐matched group from the general population.