Background: Patients with chronic conditions bear a burden when managing several long-term medications. However, little research has been done on how it affects patients’ day-to-day activities. This study looked at how several parts of everyday living were affected by cardiovascular medicine and how adherent and non-adherent individuals differed in these areas. Method: Patients utilizing cardiovascular medicine who were 45 years of age or older participated in this cross-sectional study. Patients who were adherent and non-adherent, as determined by pharmacy refill data, were divided into two equal group sizes. The Living with Medicines Questionnaire was used to gather information about how patients’ daily lives were affected by their usage of medications.Results:A total of 196 patients took part, of whom 96 were non-adherent. A significant percentage of patients reported that their daily lives were burdened by medication-related issues. Accepting long-term drug use, worries or discontent with medications, how medications affect social and everyday life, and how to connect and communicate with healthcare providers were the main causes of this stress. When evaluating the effect on patients’ daily lives between adherent and nonadherent patients, no statistically significant findings were discovered. Conclusion:Health care professionals should be aware of how taking multiple long-term medications affects patients’ daily lives and try to reduce the burden that comes with taking medications by strengthening their relationships with patients and providing appropriate treatment information that takes into account each patient’s unique situation. This could make it easier for patients to incorporate long-term medication use into their regular routines. ; Background: Patients with chronic conditions bear a burden when managing several long-term medications. However, little research has been done on how it affects patients’ day-to-day activities. This study looked at how several parts of everyday living were affected by ...