Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 × 10
| Verfasser: |
van der Valk, R.J.P.
Kreiner-Moller, E.
Kooijman, M.N.
Guxens, M.
Stergiakouli, E.
Saaf, A.
Bradfield, J.P.
Geller, F.
Hayes, M.G.
Cousminer, D.L.
Koerner, A.
Thiering, E.
Curtin, J.A.
Myhre, R.
Huikari, V.
Joro, R.
Kerkhof, M.
Warrington, N.M.
Pitkanen, N.
Ntalla, I.
Horikoshi, M.
Veijola, R.
Freathy, R.M.
Teo, Y.
Barton, S.J.
Evans, D.M.
Kemp, J.P.
St Pourcain, B.
Ring, S.M.
Smith, G.D.
Bergstrom, A.
Kull, I.
Hakonarson, H.
Mentch, F.D.
Bisgaard, H.
Chawes, B.
Stokholm, J.
Waage, J.
Eriksen, P.
Sevelsted, A.
Melbye, M.
van Duijn, C.M.
Medina-Gomez, C.
Hofman, A.
de Jongste, J.C.
Taal, H.R.
Uitterlinden, A. G.
Armstrong, L.L.
Eriksson, J.
Palotie, A.
Bustamante, M.
Estivill, X.
Gonzalez, J.R.
Llop, S.
Kiess, W.
Mahajan, A.
Flexeder, C.
Tiesler, C.M.T.
Murray, C.S.
Simpson, A.
Magnus, P.
Sengpiel, V.
Hartikainen, A.
Keinanen-Kiukaanniemi, S.
Lewin, A.
Alves, A.D.S.C.
Blakemore, A.I.
Buxton, J.L.
Kaakinen, M.
Rodriguez, A.
Sebert, S.
Vaarasmaki, M.
Lakka, T.
Lindi, V.
Gehring, U.
Postma, D.S.
Ang, W.
Newnham, J.P.
Lyytikainen, L.
Pahkala, K.
Raitakari, O.T.
Panoutsopoulou, K.
Zeggini, E.
Boomsma, D.I.
Groen-Blokhuis, M.M.
Ilonen, J.
Franke, L.
Hirschhorn, J.N.
Pers, T.H.
Liang, L.
Huang, J.
Hocher, B.
Knip, M.
Saw, S.
Holloway, J.W.
Melen, E.
Grant, S.F.A.
Feenstra, B.
Lowe, W.L.
Widen, E.
Sergeyev, E.
Grallert, H.
Custovic, A.
Jacobsson, B.
Jarvelin, M.
Atalay, M.
Koppelman, G.H.
Pennell, C.E.
Niinikoski, H.
Dedoussis, G.V.
McCarthy, M.I.
Frayling, T.M.
Sunyer, J.
Timpson, N.J.
Rivadeneira, F.
Bonnelykke, K.
Jaddoe, V.W.V. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2015 |
| Reihe/Periodikum: |
van der Valk , R J P , Kreiner-Moller , E , Kooijman , M N , Guxens , M , Stergiakouli , E , Saaf , A , Bradfield , J P , Geller , F , Hayes , M G , Cousminer , D L , Koerner , A , Thiering , E , Curtin , J A , Myhre , R , Huikari , V , Joro , R , Kerkhof , M , Warrington , N M , Pitkanen , N , Ntalla , I , Horikoshi , M , Veijola , R , Freathy , R M , Teo , Y , Barton , S J , Evans , D M , Kemp , J P , St Pourcain , B , Ring , S M , Smith , G D , Bergstrom , A , Kull , I , Hakonarson , H , Mentch , F D , Bisgaard , H , Chawes , B , Stokholm , J , Waage , J , Eriksen , P , Sevelsted , A , Melbye , M , van Duijn , C M , Medina-Gomez , C , Hofman , A , de Jongste , J C , Taal , H R , Uitterlinden , A G , Armstrong , L L , Eriksson , J , Palotie , A , Bustamante , M , Estivill , X , Gonzalez , J R , Llop , S , Kiess , W , Mahajan , A , Flexeder , C , Tiesler , C M T , Murray , C S , Simpson , A , Magnus , P , Sengpiel , V , Hartikainen , A , Keinanen-Kiukaanniemi , S , Lewin , A , Alves , A D S C , Blakemore , A I , Buxton , J L , Kaakinen , M , Rodriguez , A , Sebert , S , Vaarasmaki , M , Lakka , T , Lindi , V , Gehring , U , Postma , D S , Ang , W , Newnham , J P , Lyytikainen , L , Pahkala , K , Raitakari , O T , Panoutsopoulou , K , Zeggini , E , Boomsma , D I , Groen-Blokhuis , M M , Ilonen , J , Franke , L , Hirschhorn , J N , Pers , T H , Liang , L , Huang , J , Hocher , B , Knip , M , Saw , S , Holloway , J W , Melen , E , Grant , S F A , Feenstra , B , Lowe , W L , Widen , E , Sergeyev , E , Grallert , H , Custovic , A , Jacobsson , B , Jarvelin , M , Atalay , M , Koppelman , G H , Pennell , C E , Niinikoski , H , Dedoussis , G V , McCarthy , M I , Frayling , T M , Sunyer , J , Timpson , N J , Rivadeneira , F , Bonnelykke , K & Jaddoe , V W V 2015 , ' A novel common variant in DCST2 is associated with length in early life and height in adulthood ' , Human Molecular Genetics , vol. 24 , no. 4 , pp. 1155-1168 . https://doi.org/10.1093/hmg/ddu510 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29215062 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/fa50f2e0-4611-4f6d-9388-0a243811b60c |
