Recent studies have made great strides towards identifying putative genetic events underlying the evolution of the human brain and its emergent cognitive capacities. One of the most intriguing findings is the recurrent identification of adaptive evolution in genes associated with primary microcephaly, a developmental disorder characterized by severe reduction in brain size and intelligence, reminiscent of the early hominid condition. This has led to the hypothesis that the adaptive evolution of these genes has contributed to the emergence of modern human cognition. As with other candidate loci... Mehr ...
Verfasser: |
Mekel-Bobrov, N.
Posthuma, D.
Gilbert, S.L.
Lind, P.
Gosso, M.F.
Luciano, M.
Harris, S.E.
Bates, T.C.
Polderman, T.J.C.
Whalley, L.J.
Fox, H.
Starr, J.M.
Evans, P.D.
Montgomery, GW
Fernandes, C.
Heutink, P.
Martin, N.G.
Boomsma, D.I.
Deary, I.J.
Wright, M.J.
de Geus, E.J.C.
Lahn, B.T. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2007 |
Reihe/Periodikum: |
Mekel-Bobrov , N , Posthuma , D , Gilbert , S L , Lind , P , Gosso , M F , Luciano , M , Harris , S E , Bates , T C , Polderman , T J C , Whalley , L J , Fox , H , Starr , J M , Evans , P D , Montgomery , GW , Fernandes , C , Heutink , P , Martin , N G , Boomsma , D I , Deary , I J , Wright , M J , de Geus , E J C & Lahn , B T 2007 , ' The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. ' , Human Molecular Genetics , vol. 16 , no. 6 , pp. 600-608 . https://doi.org/10.1093/hmg/ddl487 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-29213507 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/2b814ce0-af1a-4e97-90e4-62e9cbb9acd0 |