Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals:A Meta-Analysis
Importance: Adult mood disorders are often preceded by behavioral and emotional problems in childhood. It is yet unclear what explains the associations between childhood psychopathology and adult traits. Objective: To investigate whether genetic risk for adult mood disorders and associated traits is associated with childhood disorders. Design, Setting, and Participants: This meta-analysis examined data from 7 ongoing longitudinal birth and childhood cohorts from the UK, the Netherlands, Sweden, Norway, and Finland. Starting points of data collection ranged from July 1985 to April 2002. Partici... Mehr ...
| Verfasser: |
Akingbuwa, Wonuola A
Hammerschlag, Anke R
Jami, Eshim S
Baselmans, Bart
Hagenbeek, Fiona A
Hottenga, Jouke-Jan
Mbarek, Hamdi
Boomsma, Dorret I
Nivard, Michel G
Bartels, Meike
Middeldorp, Christel M |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2020 |
| Reihe/Periodikum: |
Akingbuwa , W A , Hammerschlag , A R , Jami , E S , Baselmans , B , Hagenbeek , F A , Hottenga , J-J , Mbarek , H , Boomsma , D I , Nivard , M G , Bartels , M , Middeldorp , C M & Bipolar Disorder and Major Depressive Disorder Working Groups of the Psychiatric Genomics Consortium 2020 , ' Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals : A Meta-Analysis ' , JAMA Psychiatry , vol. 77 , no. 7 , pp. 715-728 . https://doi.org/10.1001/jamapsychiatry.2020.0527 |
| Schlagwörter: |
Childhood psychopathology
/ Developmental psychopathology
/ Genetics
/ polygenic risk score (PRS)
/ Meta analysis
/ Generation R
/ TEDS
/ CATSS
/ NFBC86
/ ALSPAC
/ NTR
/ MoBa
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29213404 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/1ecd9566-2da2-4e34-bc4d-c8b35fef6a63 |
