A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490. Three independent single-nucleotide polymorphisms (SNPs) are genome-wide significant (rs9320913, rs11584700, rs4851266), and all three replicate. Estimated effects sizes are small (coefficient of determination R
| Verfasser: |
Rietveld, C.A.
Medland, S.E.
Derringer, J.
Yang, J.
Esko, T.
Martin, N.W.
Westra, H.J.
Shakhbazov, K.
Abdellaoui, A.
Agrawal, A.
Albrecht, E.
Alizadeh, BZ
Amin, N.
Barnard, J.
Baumeister, S.E.
Benke, K.S.
Bielak, L.F.
Boatman, J.A.
Boyle, P.A.
Davies, G.
de Leeuw, C.A.
Eklund, N.
Evans, D.S.
Fehrmann, R.S.
Fischer, K.
Gieger, C.
Gjessing, H.K.
Hägg, S.
Harris, J.R.
Hayward, C.
Holzapfel, C.
Ibrahim-Verbaas, C.A.
Ingelsson, E.
Jacobsson, B.
Joshi, P.K.
Jugessur, A.
Kaakinen, M.
Kanoni, S.
Karjalainen, J.
Kolcic, I.
Kristiansson, K.
Kutalik, Z.
Lahti, J.
Lee, S.H.
Lin, P.
Lind, P.A.
Liu, Y.
Lohman, K.
Loitfelder, M.
McMahon, G.
Vidal, P.M.
Meirelles, O.
Milani, L.
Myhre, R.
Nuotio, M.L.
Oldmeadow, C.J.
Petrovic, K.E.
Peyrot, W.J.
Polasek, O.
Quaye, L.
Reinmaa, E.
Rice, J.P.
Rizzi, T.S.
Schmidt, H.
Schmidt, R.
Smith, A.V.
Smith, J.A.
Tanaka, T.
Terracciano, A.
van der Loos, M.J.
Vitart, V.
Völzke, H.
Wellmann, J.
Yu, L.
Zhao, W.
Allik, J.
Attia, J.R.
Bandinelli, S.
Bastardot, F.
Beauchamp, J.
Bennett, D.A.
Berger, K.
Bierut, L.J.
Boomsma, D.I.
Bültmann, U.
Campbell, H.
Chabris, C.F.
Cherkas, L.
Chung, M.K.
Cucca, F.
de Andrade, M.
Jager, P.L.
de Neve, J.E.
Deary, I.J.
Dedoussis, G.V.
Deloukas, P.
Dimitriou, M.
Eiriksdottir, G.
Elderson, M.F.
Eriksson, J.G.
Evans, D.M.
Faul, J.D.
Ferrucci, L.
Garcia, M.E.
Grönberg, H.
Gudnason, V.
Hall, P.
Harris, J.M.
Harris, T.B.
Hastie, N.D.
Heath, A.C.
Hernandez, D.G.
Hoffmann, W.
Hofman, A.
Holle, R.
Holliday, E.G.
Hottenga, J.J.
Iacono, W.G.
Illig, T.
Järvelin, M.R.
Kähönen, M.
Kaprio, J.
Kirkpatrick, R.M.
Kowgier, M.
Latvala, A.
Launer, L.J.
Lawlor, D.A.
Lehtimäki, T.
Li, J.
Lichtenstein, P.
Lichtner, P.
Liewald, D.C.
Madden, P.A.F.
Magnusson, P.K.E.
Mäkinen, T.E.
Masala, M.
McGue, M.
Metspalu, A.
Mielck, A.
Miller, M.B.
Montgomery, G.W.
Mukherjee, S.
Nyholt, DR
Oostra, B.A.
Palmer, L.J.
Palotie, A.
Penninx, B.W.J.H.
Perola, M.
Peyser, P.A.
Preisig, M.
Räikkönen, K.
Raitakari, O.T.
Realo, A.
Ring, S.M.
Ripatti, S.
Rivadeneira, F.
Rudan, I.
Rustichini, A.
Salomaa, V.
Sarin, A.P.
Schlessinger, D.
Scott, R.J.
Snieder, H.
St Pourcain, B.
Starr, J.M.
Sul, J.H.
Surakka, I.
Svento, R.
Teumer, A.
Tiemeier, H.
van Rooij, F.J.
Wagoner, D.R.
Vartiainen, E.
Viikari, J.
Vollenweider, P.
Vonk, J.M.
Waeber, G.
Weir, D.R.
Wichmann, H.E.
Widen, E.
Willemsen, G.
Wilson, J.F.
Wright, A.F.
Conley, D.
Davey Smith, G.
Franke, L.
Groenen, P.J.F.
Johannesson, M.
Kardia, S.
Krueger, R.F.
Laibson, D.
Martin, N.G.
Meyer, M.N.
Posthuma, D.
Thurik, A.R.
Timpson, N.J.
Uitterlinden, A.G.
van Duijn, C.M.
Visscher, P.M.
Benjamin, D.J.
Cesarini, D.
Koellinger, P.D. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2013 |
| Reihe/Periodikum: |
Rietveld , C A , Medland , S E , Derringer , J , Yang , J , Esko , T , Martin , N W , Westra , H J , Shakhbazov , K , Abdellaoui , A , Agrawal , A , Albrecht , E , Alizadeh , BZ , Amin , N , Barnard , J , Baumeister , S E , Benke , K S , Bielak , L F , Boatman , J A , Boyle , P A , Davies , G , de Leeuw , C A , Eklund , N , Evans , D S , Fehrmann , R S , Fischer , K , Gieger , C , Gjessing , H K , Hägg , S , Harris , J R , Hayward , C , Holzapfel , C , Ibrahim-Verbaas , C A , Ingelsson , E , Jacobsson , B , Joshi , P K , Jugessur , A , Kaakinen , M , Kanoni , S , Karjalainen , J , Kolcic , I , Kristiansson , K , Kutalik , Z , Lahti , J , Lee , S H , Lin , P , Lind , P A , Liu , Y , Lohman , K , Loitfelder , M , McMahon , G , Vidal , P M , Meirelles , O , Milani , L , Myhre , R , Nuotio , M L , Oldmeadow , C J , Petrovic , K E , Peyrot , W J , Polasek , O , Quaye , L , Reinmaa , E , Rice , J P , Rizzi , T S , Schmidt , H , Schmidt , R , Smith , A V , Smith , J A , Tanaka , T , Terracciano , A , van der Loos , M J , Vitart , V , Völzke , H , Wellmann , J , Yu , L , Zhao , W , Allik , J , Attia , J R , Bandinelli , S , Bastardot , F , Beauchamp , J , Bennett , D A , Berger , K , Bierut , L J , Boomsma , D I , Bültmann , U , Campbell , H , Chabris , C F , Cherkas , L , Chung , M K , Cucca , F , de Andrade , M , Jager , P L , de Neve , J E , Deary , I J , Dedoussis , G V , Deloukas , P , Dimitriou , M , Eiriksdottir , G , Elderson , M F , Eriksson , J G , Evans , D M , Faul , J D , Ferrucci , L , Garcia , M E , Grönberg , H , Gudnason , V , Hall , P , Harris , J M , Harris , T B , Hastie , N D , Heath , A C , Hernandez , D G , Hoffmann , W , Hofman , A , Holle , R , Holliday , E G , Hottenga , J J , Iacono , W G , Illig , T , Järvelin , M R , Kähönen , M , Kaprio , J , Kirkpatrick , R M , Kowgier , M , Latvala , A , Launer , L J , Lawlor , D A , Lehtimäki , T , Li , J , Lichtenstein , P , Lichtner , P , Liewald , D C , Madden , P A F , Magnusson , P K E , Mäkinen , T E , Masala , M , McGue , M , Metspalu , A , Mielck , A , Miller , M B , Montgomery , G W , Mukherjee , S , Nyholt , DR , Oostra , B A , Palmer , L J , Palotie , A , Penninx , B W J H , Perola , M , Peyser , P A , Preisig , M , Räikkönen , K , Raitakari , O T , Realo , A , Ring , S M , Ripatti , S , Rivadeneira , F , Rudan , I , Rustichini , A , Salomaa , V , Sarin , A P , Schlessinger , D , Scott , R J , Snieder , H , St Pourcain , B , Starr , J M , Sul , J H , Surakka , I , Svento , R , Teumer , A , Tiemeier , H , van Rooij , F J , Wagoner , D R , Vartiainen , E , Viikari , J , Vollenweider , P , Vonk , J M , Waeber , G , Weir , D R , Wichmann , H E , Widen , E , Willemsen , G , Wilson , J F , Wright , A F , Conley , D , Davey Smith , G , Franke , L , Groenen , P J F , Johannesson , M , Kardia , S , Krueger , R F , Laibson , D , Martin , N G , Meyer , M N , Posthuma , D , Thurik , A R , Timpson , N J , Uitterlinden , A G , van Duijn , C M , Visscher , P M , Benjamin , D J , Cesarini , D & Koellinger , P D 2013 , ' GWAS of 126559 Individuals Identifies Genetic Variants Associated with Educational Attainment ' , Science , vol. 340 , no. 6139 , pp. 1467-1471 . https://doi.org/10.1126/science.1235488 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29213156 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/0963b7a9-27a9-4cbb-a429-bffdbd58c1fa |
