Objectives: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. Design: Mendelian randomisation meta-analyses using a genetic variant (rs16969968/rs1051730 in the CHRNA5-CHRNA3-CHRNB4 gene region) as a proxy for smoking heaviness, of the associations of smoking heaviness with a range of adiposity phenotypes. Participants:148 731 current, former and neversmokers of European ancestry aged.16 years from 29 studies in the consortium for Causal Analysis Rese... Mehr ...
| Verfasser: |
Morris, R.W.
Taylor, A.E.
Fluharty, M.E.
Bjorngaard, J.H.
Asvold, B.O.
Elvestad Gabrielsen, M.
Campbell, A.
Marioni, R.
Kumari, M.
Korhonen, T.
Männistö, S.
Marques-Vidal, P.
Kaakinen, M.
Cavadino, A.
Postmus, I.
Husemoen, L.L.N.
Skaaby, T.
Ahluwalia, T.S.
Treur, J.L.
Willemsen, G.
Dale, C.
Wannamethee, S.G.
Lahti, J.
Palotie, A.
Räikkönen, K.
McConnachie, A.
Padmanabhan, S.
Wong, A.
Dalgard, C.
Paternoster, L.
Ben-Shlomo, Y.
Tyrrell, J.
Horwood, J.
Fergusson, D.M.
Kennedy, M.A.
Nohr, E.A.
Christiansen, L.
Kyvik, K.O.
Kuh, D
Watt, G.
Eriksson, J.G.
Whincup, P.H.
Vink, J.M.
Boomsma, D.I.
Davey Smith, G.
Lawlor, D.
Linneberg, A.
Ford, I.
Jukema, J.W.
Power, C.
Hyppönen, E.
Jarvelin, M.R.
Preisig, M.
Borodulin, K.
Kaprio, J.
Kivimaki, M.
Smith, B.H.
Hayward, C.
Romundstad, P.R.
Sørensen, T.I.A.
Munafò, M.
Sattar, N. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2015 |
| Reihe/Periodikum: |
Morris , R W , Taylor , A E , Fluharty , M E , Bjorngaard , J H , Asvold , B O , Elvestad Gabrielsen , M , Campbell , A , Marioni , R , Kumari , M , Korhonen , T , Männistö , S , Marques-Vidal , P , Kaakinen , M , Cavadino , A , Postmus , I , Husemoen , L L N , Skaaby , T , Ahluwalia , T S , Treur , J L , Willemsen , G , Dale , C , Wannamethee , S G , Lahti , J , Palotie , A , Räikkönen , K , McConnachie , A , Padmanabhan , S , Wong , A , Dalgard , C , Paternoster , L , Ben-Shlomo , Y , Tyrrell , J , Horwood , J , Fergusson , D M , Kennedy , M A , Nohr , E A , Christiansen , L , Kyvik , K O , Kuh , D , Watt , G , Eriksson , J G , Whincup , P H , Vink , J M , Boomsma , D I , Davey Smith , G , Lawlor , D , Linneberg , A , Ford , I , Jukema , J W , Power , C , Hyppönen , E , Jarvelin , M R , Preisig , M , Borodulin , K , Kaprio , J , Kivimaki , M , Smith , B H , Hayward , C , Romundstad , P R , Sørensen , T I A , Munafò , M & Sattar , N 2015 , ' Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium ' , BMJ Open , vol. 5 , no. 8 , pp. e008808 . https://doi.org/10.1136/bmjopen-2015-008808 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29213111 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/0312f316-3225-4303-a160-22a2ee1b9914 |
