Aggressive behaviour in childhood and adolescence:the role of smoking during pregnancy, evidence from four twin cohorts in the EU-ACTION consortium

BACKGROUND: Maternal smoking during pregnancy (MSDP) has been linked to offspring's externalizing problems. It has been argued that socio-demographic factors (e.g. maternal age and education), co-occurring environmental risk factors, or pleiotropic genetic effects may account for the association between MSDP and later outcomes. This study provides a comprehensive investigation of the association between MSDP and a single harmonized component of externalizing: aggressive behaviour, measured throughout childhood and adolescence. METHODS: Data came from four prospective twin cohorts - Twins Early... Mehr ...

Verfasser: Malanchini, Margherita
Smith-Woolley, Emily
Ayorech, Ziada
Rimfeld, Kaili
Krapohl, Eva
Vuoksimaa, Eero
Korhonen, Tellervo
Bartels, Meike
van Beijsterveldt, Toos C E M
Rose, Richard J
Lundström, Sebastian
Anckarsäter, Henrik
Kaprio, Jaakko
Lichtenstein, Paul
Boomsma, Dorret I
Plomin, Robert
Dokumenttyp: Artikel
Erscheinungsdatum: 2019
Reihe/Periodikum: Malanchini , M , Smith-Woolley , E , Ayorech , Z , Rimfeld , K , Krapohl , E , Vuoksimaa , E , Korhonen , T , Bartels , M , van Beijsterveldt , T C E M , Rose , R J , Lundström , S , Anckarsäter , H , Kaprio , J , Lichtenstein , P , Boomsma , D I & Plomin , R 2019 , ' Aggressive behaviour in childhood and adolescence : the role of smoking during pregnancy, evidence from four twin cohorts in the EU-ACTION consortium ' , Psychological Medicine , vol. 49 , no. 4 , pp. 646-654 . https://doi.org/10.1017/S0033291718001344
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) / /dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions / name=SDG 16 - Peace / Justice and Strong Institutions / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29212716
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://research.vu.nl/en/publications/d05ccd75-a2bd-47ca-893f-9f0520de098f

BACKGROUND: Maternal smoking during pregnancy (MSDP) has been linked to offspring's externalizing problems. It has been argued that socio-demographic factors (e.g. maternal age and education), co-occurring environmental risk factors, or pleiotropic genetic effects may account for the association between MSDP and later outcomes. This study provides a comprehensive investigation of the association between MSDP and a single harmonized component of externalizing: aggressive behaviour, measured throughout childhood and adolescence. METHODS: Data came from four prospective twin cohorts - Twins Early Development Study, Netherlands Twin Register, Childhood and Adolescent Twin Study of Sweden, and FinnTwin12 study - who collaborate in the EU-ACTION consortium. Data from 30 708 unrelated individuals were analysed. Based on item level data, a harmonized measure of aggression was created at ages 9-10; 12; 14-15 and 16-18. RESULTS: MSDP predicted aggression in childhood and adolescence. A meta-analysis across the four samples found the independent effect of MSDP to be 0.4% (r = 0.066), this remained consistent when analyses were performed separately by sex. All other perinatal factors combined explained 1.1% of the variance in aggression across all ages and samples (r = 0.112). Paternal smoking and aggressive parenting strategies did not account for the MSDP-aggression association, consistent with the hypothesis of a small direct link between MSDP and aggression. CONCLUSIONS: Perinatal factors, including MSDP, account for a small portion of the variance in aggression in childhood and adolescence. Later experiences may play a greater role in shaping adolescents' aggressive behaviour.