INTRODUCTION: FTND (Fagerstrӧm test for nicotine dependence) and TTFC (time to smoke first cigarette in the morning) are common measures of nicotine dependence (ND). However, genome-wide meta-analysis for these phenotypes has not been reported. METHODS: Genome-wide meta-analyses for FTND (N = 19,431) and TTFC (N = 18,567) phenotypes were conducted for adult smokers of European ancestry from 14 independent cohorts. RESULTS: We found that SORBS2 on 4q35 (p = 4.05 × 10-8), BG182718 on 11q22 (p = 1.02 × 10-8), and AA333164 on 14q21 (p = 4.11 × 10-9) were associated with TTFC phenotype. We attempte... Mehr ...
| Verfasser: |
Chen, Jingchun
Loukola, Anu
Gillespie, Nathan A
Peterson, Roseann
Jia, Peilin
Riley, Brien
Maes, Hermine
Dick, Daniella M
Kendler, Kenneth S
Damaj, M Imad
Miles, Michael F
Zhao, Zhongming
Li, Ming D
Vink, Jacqueline M
Minica, Camelia C
Willemsen, Gonneke
Boomsma, Dorret I
Qaiser, Beenish
Madden, Pamela A F
Korhonen, Tellervo
Jousilahti, Pekka
Hällfors, Jenni
Gelernter, Joel
Kranzler, Henry R
Sherva, Richard
Farrer, Lindsay
Maher, Brion
Vanyukov, Michael
Taylor, Michelle
Ware, Jenifer J
Munafò, Marcus R
Lutz, Sharon M
Hokanson, John E
Gu, Fangyi
Landi, Maria T
Caporaso, Neil E
Hancock, Dana B
Gaddis, Nathan C
Baker, Timothy B
Bierut, Laura J
Johnson, Eric O
Chenoweth, Meghan
Lerman, Caryn
Tyndale, Rachel
Kaprio, Jaakko
Chen, Xiangning |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2020 |
| Reihe/Periodikum: |
Chen , J , Loukola , A , Gillespie , N A , Peterson , R , Jia , P , Riley , B , Maes , H , Dick , D M , Kendler , K S , Damaj , M I , Miles , M F , Zhao , Z , Li , M D , Vink , J M , Minica , C C , Willemsen , G , Boomsma , D I , Qaiser , B , Madden , P A F , Korhonen , T , Jousilahti , P , Hällfors , J , Gelernter , J , Kranzler , H R , Sherva , R , Farrer , L , Maher , B , Vanyukov , M , Taylor , M , Ware , J J , Munafò , M R , Lutz , S M , Hokanson , J E , Gu , F , Landi , M T , Caporaso , N E , Hancock , D B , Gaddis , N C , Baker , T B , Bierut , L J , Johnson , E O , Chenoweth , M , Lerman , C , Tyndale , R , Kaprio , J & Chen , X 2020 , ' Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes ' , Nicotine and Tobacco Research , vol. 22 , no. 6 , pp. 900-909 . https://doi.org/10.1093/ntr/ntz099 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29212688 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/cc78b1b7-ab48-4690-9a21-73cd1e35be33 |
