Many hemostatic factors are associated with age and age-related diseases; however, much remains unknown about the biological mechanisms linking aging and hemostatic factors. DNA methylation is a novel means by which to assess epigenetic aging, which is a measure of age and the aging processes as determined by altered epigenetic states. We used a meta-analysis approach to examine the association between measures of epigenetic aging and hemostatic factors, as well as a clotting time measure. For fibrinogen, we performed European and African ancestry–specific meta-analyses which were then combine... Mehr ...
| Verfasser: |
Ward-Caviness, Cavin K.
Huffman, Jennifer E.
Everett, Karl
Germain, Marine
Van Dongen, Jenny
Hill, W. David
Jhun, Min A.
Brody, Jennifer A.
Ghanbari, Mohsen
Du, Lei
Roetker, Nicholas S.
De Vries, Paul S.
Waldenberger, Melanie
Gieger, Christian
Wolf, Petra
Prokisch, Holger
Koenig, Wolfgang
O’Donnell, Christopher J.
Levy, Daniel
Liu, Chunyu
Truong, Vinh
Wells, Philip S.
Trégouët, David Alexandre
Tang, Weihong
Morrison, Alanna C.
Boerwinkle, Eric
Wiggins, Kerri L.
McKnight, Barbara
Guo, Xiuqing
Psaty, Bruce M.
Sotoodenia, Nona
Boomsma, Dorret I.
Willemsen, Gonneke
Ligthart, Lannie
Deary, Ian J.
Zhao, Wei
Ware, Erin B.
Kardia, Sharon L.R.
Van Meurs, Joyce B.J.
Uitterlinden, Andre G.
Franco, Oscar H.
Eriksson, Per
Franco-Cereceda, Anders
Pankow, James S.
Johnson, Andrew D.
Gagnon, France
Morange, Pierre Emmanuel
De Geus, Eco J.C.
Starr, John M.
Smith, Jennifer A.
Dehghan, Abbas
Björck, Hanna M.
Smith, Nicholas L.
Peters, Annette |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2018 |
| Reihe/Periodikum: |
Ward-Caviness , C K , Huffman , J E , Everett , K , Germain , M , Van Dongen , J , Hill , W D , Jhun , M A , Brody , J A , Ghanbari , M , Du , L , Roetker , N S , De Vries , P S , Waldenberger , M , Gieger , C , Wolf , P , Prokisch , H , Koenig , W , O’Donnell , C J , Levy , D , Liu , C , Truong , V , Wells , P S , Trégouët , D A , Tang , W , Morrison , A C , Boerwinkle , E , Wiggins , K L , McKnight , B , Guo , X , Psaty , B M , Sotoodenia , N , Boomsma , D I , Willemsen , G , Ligthart , L , Deary , I J , Zhao , W , Ware , E B , Kardia , S L R , Van Meurs , J B J , Uitterlinden , A G , Franco , O H , Eriksson , P , Franco-Cereceda , A , Pankow , J S , Johnson , A D , Gagnon , F , Morange , P E , De Geus , E J C , Starr , J M , Smith , J A , Dehghan , A , Björck , H M , Smith , N L & Peters , A 2018 , ' DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis ' , Blood , vol. 132 , no. 17 , pp. 1842-1850 . https://doi.org/10.1182/blood-2018-02-831347 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29211528 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/5127e7d5-7411-43a3-94b4-12e7ada33fbc |
