The heritability of beta cell function parameters in a mixed meal test design

Aims/hypothesis: We estimated the heritability of individual differences in beta cell function after a mixed meal test designed to assess a wide range of classical and model-derived beta cell function parameters. Methods: A total of 183 healthy participants (77 men), recruited from the Netherlands Twin Register, took part in a 4 h protocol, which included a mixed meal test. Participants were Dutch twin pairs and their siblings, aged 20 to 49 years. All members within a family were of the same sex. Insulin sensitivity, insulinogenic index, insulin response and postprandial glycaemia were assess... Mehr ...

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Verfasser: Simonis-Bik, A.M.C.
Boomsma, D.I.
Dekker, J.M.
Diamant, M.
de Geus, E.J.C.
Hart, L.M.
Heine, R.J.
Kramer, M.H.H.
Maassen, J.A.
Mari, A.
Tura, A.
Willemsen, G.
Eekhoff, E.M.W.
Dokumenttyp: Artikel
Erscheinungsdatum: 2011
Reihe/Periodikum: Simonis-Bik , A M C , Boomsma , D I , Dekker , J M , Diamant , M , de Geus , E J C , Hart , L M , Heine , R J , Kramer , M H H , Maassen , J A , Mari , A , Tura , A , Willemsen , G & Eekhoff , E M W 2011 , ' The heritability of beta cell function parameters in a mixed meal test design ' , Diabetologia , vol. 54 , no. 5 , pp. 1043-1051 . https://doi.org/10.1007/s00125-011-2060-5
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29211090
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/1f87fd1f-7787-400a-aa1a-6a3adb1f59b1