Structural brain changes that occur during development and ageing are related to mental health and general cognitive functioning. Individuals differ in the extent to which their brain volumes change over time, but whether these differences can be attributed to differences in their genotypes has not been widely studied. Here we estimate heritability (h(2) ) of changes in global and subcortical brain volumes in five longitudinal twin cohorts from across the world and in different stages of the lifespan (N = 861). Heritability estimates of brain changes were significant and ranged from 16% (cauda... Mehr ...
| Verfasser: |
Brouwer, Rachel M
Panizzon, Matthew S
Glahn, David C
Hibar, Derrek P
Hua, Xue
Jahanshad, Neda
Abramovic, Lucija
De Zubicaray, Greig I
Franz, Carol E
Hansell, Narelle K
Hickie, Ian B
Koenis, Marinka M G
Martin, Nicholas G
Mather, Karen A
McMahon, Katie L
Schnack, Hugo G
Strike, Lachlan T
Swagerman, Suzanne C
Thalamuthu, Anbupalam
Wen, Wei
Gilmore, John H
Gogtay, Nitin
Kahn, René S
Sachdev, Perminder S
Wright, Margaret J
Boomsma, Dorret I
Kremen, William S
Thompson, Paul M
Hulshoff Pol, Hilleke E |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2017 |
| Reihe/Periodikum: |
Brouwer , R M , Panizzon , M S , Glahn , D C , Hibar , D P , Hua , X , Jahanshad , N , Abramovic , L , De Zubicaray , G I , Franz , C E , Hansell , N K , Hickie , I B , Koenis , M M G , Martin , N G , Mather , K A , McMahon , K L , Schnack , H G , Strike , L T , Swagerman , S C , Thalamuthu , A , Wen , W , Gilmore , J H , Gogtay , N , Kahn , R S , Sachdev , P S , Wright , M J , Boomsma , D I , Kremen , W S , Thompson , P M & Hulshoff Pol , H E 2017 , ' Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes : Results of the ENIGMA plasticity working group ' , Human Brain Mapping , vol. 38 , no. 9 , pp. 4444-4458 . https://doi.org/10.1002/hbm.23672 |
| Schlagwörter: |
Journal Article
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29210814 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/16031ceb-cc57-4486-b708-575ca1835b16 |
