Genome-wide analyses of borderline personality features
The heritability of borderline personality (BP) features has been established in multiple twin and family studies. Using data from the borderline subscale of the Personality Assessment Inventory Borderline Features Scale (PAI-BOR) collected in two Dutch cohorts (N=7125), the Netherlands Twin Register and The Netherlands Study of Depression and Anxiety, we show that heritability of the PAI-BOR total score using genome-wide single-nucleotide polymorphism (SNPs) is estimated at 23%, and that the genetic variance is substantially higher in affect instability items compared with the other three sub... Mehr ...
Verfasser: |
Lubke, G.H.
Laurin, C.
Amin, N.
Hottenga, J.J.
Willemsen, G.
Grootheest, G.
Abdellaoui, A.
Karssen, L.C.
Oostra, B.A.
van Duijn, C.M.
Penninx, B.W.J.H.
Boomsma, D.I. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2014 |
Reihe/Periodikum: |
Lubke , G H , Laurin , C , Amin , N , Hottenga , J J , Willemsen , G , Grootheest , G , Abdellaoui , A , Karssen , L C , Oostra , B A , van Duijn , C M , Penninx , B W J H & Boomsma , D I 2014 , ' Genome-wide analyses of borderline personality features ' , Molecular Psychiatry , vol. 19 , no. 8 , pp. 923-929 . https://doi.org/10.1038/mp.2013.109 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-29210739 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/0e542e1f-f257-4a74-ba88-c3d4acddd136 |