Mpox outbreak in the Netherlands, 2022:public health response, characteristics of the first 1,000 cases and protection of the first-generation smallpox vaccine

In early May 2022, a global outbreak of mpox started among persons without travel history to regions known to be enzootic for monkeypox virus (MPXV). On 8 August 2022, the Netherlands reported its 1,000th mpox case, representing a cumulative incidence of 55 per million population, one of the highest cumulative incidences worldwide. We describe characteristics of the first 1,000 mpox cases in the Netherlands, reported between 20 May and 8 August 2022, within the context of the public health response. These cases were predominantly men who have sex with men aged 31-45 years. The vast majority of... Mehr ...

Verfasser: van Ewijk, Catharina E.
Miura, Fuminari
van Rijckevorsel, Gini
de Vries, Henry Jc
Welkers, Matthijs Ra
van den Berg, Oda E.
Friesema, Ingrid Hm
van den Berg, Patrick R.
Dalhuisen, Thomas
Wallinga, Jacco
Brandwagt, Diederik
van Cleef, Brigitte Agl
Vennema, Harry
Voordouw, Bettie
Koopmans, Marion
van der Eijk, Annemiek A.
Swaan, Corien M.
Te Wierik, Margreet Jm
Leenstra, Tjalling
Op de Coul, Eline
Franz, Eelco
Dokumenttyp: Artikel
Erscheinungsdatum: 2023
Reihe/Periodikum: Dutch Mpox Response Team , Members of the Dutch Mpox Response Team , van Ewijk , C E , Miura , F , van Rijckevorsel , G , de Vries , H J , Welkers , M R , van den Berg , O E , Friesema , I H , van den Berg , P R , Dalhuisen , T , Wallinga , J , Brandwagt , D , van Cleef , B A , Vennema , H , Voordouw , B , Koopmans , M , van der Eijk , A A , Swaan , C M , Te Wierik , M J , Leenstra , T , Op de Coul , E & Franz , E 2023 , ' Mpox outbreak in the Netherlands, 2022 : public health response, characteristics of the first 1,000 cases and protection of the first-generation smallpox vaccine ' , Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin , vol. 28 , no. 12 , 2200772 . https://doi.org/10.2807/1560-7917.ES.2023.28.12.2200772
Schlagwörter: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29207559
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://pure.eur.nl/en/publications/8c8da213-3aec-4d64-b4fd-851f661b8b87

In early May 2022, a global outbreak of mpox started among persons without travel history to regions known to be enzootic for monkeypox virus (MPXV). On 8 August 2022, the Netherlands reported its 1,000th mpox case, representing a cumulative incidence of 55 per million population, one of the highest cumulative incidences worldwide. We describe characteristics of the first 1,000 mpox cases in the Netherlands, reported between 20 May and 8 August 2022, within the context of the public health response. These cases were predominantly men who have sex with men aged 31-45 years. The vast majority of infections were acquired through sexual contact with casual partners in private or recreational settings including LGBTQIA+ venues in the Netherlands. This indicates that, although some larger upsurges occurred from point-source and/or travel-related events, the outbreak was mainly characterised by sustained transmission within the Netherlands. In addition, we estimated the protective effect of first-generation smallpox vaccine against moderate/severe mpox and found a vaccine effectiveness of 58% (95% CI: 17-78%), suggesting moderate protection against moderate/severe mpox symptoms on top of any possible protection by this vaccine against MPXV infection and disease. Communication with and supporting the at-risk population in following mitigation measures remains essential.