The effect of remote ischaemic preconditioning on postoperative cardiac and inflammatory biomarkers in pancreatic surgery: a randomized controlled trial

Background: Cardiac and inflammatory biomarkers have been associated with adverse outcome after major abdominal surgery. This study investigated the effect of remote ischaemic preconditioning (RIPC) on perioperative concentrations of high-sensitive cardiac troponin (hs-cTn) T and interleukin (IL) 6. Methods: Adult patients scheduled for elective pancreatic surgery between March 2017 and February 2019 were randomized to either three cycles of upper-limb ischaemia and reperfusion (each 5 min) or a sham procedure before surgery. The primary endpoint was the maximum postoperative hs-cTnT concentra... Mehr ...

Verfasser: van Zeggeren, L.
Visser, R. A.
Vernooij, L. M.
Dijkstra, I. M.
Bosma, M.
Molenaar, Q.
van Santvoort, H. C.
Noordzij, P. G.
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Schlagwörter: Aged / Biomarkers/blood / Double-Blind Method / Female / Humans / Interleukin-6/blood / Ischemic Preconditioning/methods / Linear Models / Male / Myocardial Ischemia/blood / Netherlands / Pancreaticoduodenectomy/adverse effects / Postoperative Complications/etiology / Troponin T/blood / General Medicine / Research Support / Non-U.S. Gov't / Randomized Controlled Trial / Journal Article
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29203713
Datenquelle: BASE; Originalkatalog
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Link(s) : https://dspace.library.uu.nl/handle/1874/443638