Is there still a role for nuchal translucency measurement in the changing paradigm of first trimester screening?
OBJECTIVES: To give an overview of the genetic and structural abnormalities occurring in fetuses with nuchal translucency (NT) measurement exceeding the 95th percentile at first-trimester screening and to investigate which of these abnormalities would be missed if cell-free fetal DNA (cfDNA) were used as a first-tier screening test for chromosomal abnormalities. METHODS: This is a national study including 1901 pregnancies with NT≥95th percentile referred to seven university hospitals in the Netherlands between 1 January 2010 and 1 January 2016. All cases with unknown pregnancy outcome were exc... Mehr ...
Verfasser: | |
---|---|
Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2020 |
Schlagwörter: | Abnormal Karyotype / Adolescent / Adult / Aneuploidy / Chromosome Disorders/diagnostic imaging / Congenital Abnormalities/diagnostic imaging / DiGeorge Syndrome/diagnostic imaging / Down Syndrome/diagnostic imaging / Ectodermal Dysplasia/diagnostic imaging / Facies / Failure to Thrive/diagnostic imaging / Female / Heart Defects / Congenital/diagnostic imaging / Humans / LEOPARD Syndrome/diagnostic imaging / Middle Aged / Netherlands / Noninvasive Prenatal Testing / Noonan Syndrome/diagnostic imaging / Nuchal Translucency Measurement / Pregnancy / Pregnancy Trimester / First / Trisomy 13 Syndrome/diagnostic imaging / Trisomy 18 Syndrome/diagnostic imaging / Ultrasonography / Prenatal / Young Adult / Journal Article |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-29203595 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/439151 |