Utilisation of radiotherapy in lung cancer : a scoping narrative literature review with a focus on the introduction of evidence-based therapeutic approaches in Europe

Background and purpose: The aim of this study was to review the published studies on the utilisation of radio-therapy in lung cancer (both small and non-small cell lung cancer, SCLC and NSCLC) patients in European countries with a population-based perspective. Material and methods: A literature search since January 2000 until December 2022 was carried out. Only English -published papers were included, and only European data was considered. PRISMA guidelines were followed. A scoping narrative review was undertaken due to the hetereogeneity of the published papers.Results: 38 papers were include... Mehr ...

Verfasser: Corral, Julieta
Borras, Josep M.
Lievens, Yolande
Dokumenttyp: journalarticle
Erscheinungsdatum: 2024
Schlagwörter: Medicine and Health Sciences / Radiation Oncology / Lung Cancer / Patterns of care / Utilisation / TREATMENT PATTERNS / ELDERLY-PATIENTS / BODY RADIOTHERAPY / SOUTH NETHERLANDS / STAGE / SURVIVAL / ACCESS / MANAGEMENT / TRENDS / TIME
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29197042
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://biblio.ugent.be/publication/01J0XVQQNQR612RZGWEWGS8687

Background and purpose: The aim of this study was to review the published studies on the utilisation of radio-therapy in lung cancer (both small and non-small cell lung cancer, SCLC and NSCLC) patients in European countries with a population-based perspective. Material and methods: A literature search since January 2000 until December 2022 was carried out. Only English -published papers were included, and only European data was considered. PRISMA guidelines were followed. A scoping narrative review was undertaken due to the hetereogeneity of the published papers.Results: 38 papers were included in the analysis, with the majority from the Netherlands (52.6%) and the UK (18.4%). Large variability is observed in the reported radiotherapy utilisation, around 40% for NSCLC in general and between 26 and 42% in stage I NSCLC. Stereotactic body radiotherapy (SBRT) shows a wide range of utilisation across countries and over time, from 8 to 63%. Similary, in stage III lung cancer, chemoradiotherapy (CRT) utilisation varied considerably (11-70%). Eleven studies compared radiotherapy utilisation between older and younger age-groups, showing that younger patients receive more CRT, while the opposite applies for SBRT. An widespreadlack of data on relevant covariates such as comorbidty and health-services related variables is observed. Conclusion: The actual utilisation of radiotherapy for lung cancer reported in patterns-of-care studies (POCs) is notably lower than the evidence-based optimal utilisation. Important variability is observed by country, time period, stage at diagnosis and age. A wider use of POCs should be promoted to improve our knowledge on the actual application of evidence-based treatment recommendations.