Does endometrial scratching increase the rate of spontaneous conception in couples with unexplained infertility and a good prognosis (Hunault > 30%)? Study protocol of the SCRaTCH-OFO trial:a randomized controlled trial

BACKGROUND: In the Netherlands, couples with unexplained infertility and a good prognosis to conceive spontaneously (i.e. Hunault > 30%) are advised to perform timed intercourse for at least another 6 months. If couples fail to conceive within this period, they will usually start assisted reproductive technology (ART). However, treatment of unexplained infertility by ART is empirical and can involve significant burdens. Intentional endometrial injury, also called 'endometrial scratching', has been proposed to positively affect the chance of embryo implantation in patients undergoing in vitr... Mehr ...

Verfasser: Bui, B.N.
Torrance, H.L.
Janssen, C.
Cohlen, B.
de Bruin, J.P.
den Hartog, J.E.
van der Linden, P J.Q.
Deurloo, K.L.
Maas, J.W.M.
van Oppenraaij, R.
Cantineau, A.
Lambalk, C.B.
Visser, H.
Brinkhuis, E.
van Disseldorp, J.
Schoot, B.C.
Lardenoije, C.
van Wely, M.
Eijkemans, M.J.C.
Broekmans, F.J.M.
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Reihe/Periodikum: Bui , B N , Torrance , H L , Janssen , C , Cohlen , B , de Bruin , J P , den Hartog , J E , van der Linden , P J Q , Deurloo , K L , Maas , J W M , van Oppenraaij , R , Cantineau , A , Lambalk , C B , Visser , H , Brinkhuis , E , van Disseldorp , J , Schoot , B C , Lardenoije , C , van Wely , M , Eijkemans , M J C & Broekmans , F J M 2018 , ' Does endometrial scratching increase the rate of spontaneous conception in couples with unexplained infertility and a good prognosis (Hunault > 30%)? Study protocol of the SCRaTCH-OFO trial : a randomized controlled trial ' , BMC Pregnancy and Childbirth , vol. 18 , no. 1 , 511 . https://doi.org/10.1186/s12884-018-2160-z
Schlagwörter: Endometrial injury / Endometrial receptivity / Endometrial scratch / Endometrial scratching / Expectant management / Hunault > 30% / Implantation failure / Unexplained infertility / Abortion / Spontaneous / Endometrium/surgery / Prognosis / Humans / Live Birth / Infertility / Female/therapy / Reproductive Techniques / Assisted/economics / Randomized Controlled Trials as Topic / Luteal Phase / Young Adult / Netherlands / Multicenter Studies as Topic / Adolescent / Adult / Female / Birth Rate
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29195858
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.tue.nl/en/publications/64349c2e-556c-472c-b3a8-2d8f4ceb1556