Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery:a multi-center randomized controlled trial
BACKGROUND: To determine whether intermittent intravenous (IV) paracetamol as primary analgesic would significantly reduce morphine consumption in children aged 0-3 years after cardiac surgery with cardiopulmonary bypass. METHODS: Multi-center, randomized, double-blinded, controlled trial in four level-3 Pediatric Intensive Care Units (PICU) in the Netherlands and Belgium. Inclusion period; March 2016-July 2020. Children aged 0-3 years, undergoing cardiac surgery with cardiopulmonary bypass were eligible. Patients were randomized to continuous morphine or intermittent IV paracetamol as primary... Mehr ...
| Verfasser: |
Zeilmaker-Roest, Gerdien
de Vries-Rink, Christine
van Rosmalen, Joost
van Dijk, Monique
de Wildt, Saskia N
Knibbe, Catherijne A J
Koomen, Erik
Jansen, Nicolaas J G
Kneyber, Martin C J
Maebe, Sofie
Van den Berghe, Greet
Haghedooren, Renata
Vlasselaers, Dirk
Bogers, Ad J J C
Tibboel, Dick
Wildschut, Enno D |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2024 |
| Reihe/Periodikum: |
Zeilmaker-Roest , G , de Vries-Rink , C , van Rosmalen , J , van Dijk , M , de Wildt , S N , Knibbe , C A J , Koomen , E , Jansen , N J G , Kneyber , M C J , Maebe , S , Van den Berghe , G , Haghedooren , R , Vlasselaers , D , Bogers , A J J C , Tibboel , D & Wildschut , E D 2024 , ' Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery : a multi-center randomized controlled trial ' , Critical care (London, England) , vol. 28 , 143 . https://doi.org/10.1186/s13054-024-04905-3 |
| Schlagwörter: |
Humans
/ Morphine/therapeutic use
/ Acetaminophen/therapeutic use
/ Male
/ Female
/ Infant
/ Double-Blind Method
/ Pain
/ Postoperative/drug therapy
/ Analgesics
/ Opioid/administration & dosage
/ Belgium
/ Netherlands
/ Newborn
/ Administration
/ Intravenous
/ Cardiac Surgical Procedures/methods
/ Child
/ Preschool
/ Non-Narcotic/administration & dosage
/ Intensive Care Units
/ Pediatric/organization & administration
/ Pain Measurement/methods |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29192927 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/ff8d167a-ee66-487e-8ff3-018f4efd1613 |
