Treatment Patterns and Differences in Survival of Non-Small Cell Lung Cancer Patients Between Academic and Non-Academic Hospitals in the Netherlands
Non-small cell lung cancer (NSCLC) survival is compared between patients treated in all academic (n [1289) versus all non-academic (n = 12,698) Dutch hospitals, using Kaplan-Meier estimates and a Cox proportional hazards model. For 1009 patients, treatment patterns are described. Diagnosis in an academic hospital is associated with decreased mortality. Possibilities for improvement of NSCLC care are suggested. Background: The aims of this study are to analyze differences in survival between academic and non-academic hospitals and to provide insight into treatment patterns for non-small cell lu... Mehr ...
Verfasser: | |
---|---|
Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2017 |
Reihe/Periodikum: | van der Linden , N , Bongers , M L , Coupe , V M H , Smit , E F , Groen , H J M , Welling , A , Schramel , F M N H & Uyl-de Groot , C A 2017 , ' Treatment Patterns and Differences in Survival of Non-Small Cell Lung Cancer Patients Between Academic and Non-Academic Hospitals in the Netherlands ' , Clinical lung cancer , vol. 18 , no. 5 , pp. e341-e347 . https://doi.org/10.1016/j.cllc.2015.11.011 |
Schlagwörter: | Academic medical centers / Cancer registry / General hospitals / Mortality / Therapy |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-29191423 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://hdl.handle.net/11370/74c01160-a2c8-48da-b66a-81e285c31a1a |
Non-small cell lung cancer (NSCLC) survival is compared between patients treated in all academic (n [1289) versus all non-academic (n = 12,698) Dutch hospitals, using Kaplan-Meier estimates and a Cox proportional hazards model. For 1009 patients, treatment patterns are described. Diagnosis in an academic hospital is associated with decreased mortality. Possibilities for improvement of NSCLC care are suggested. Background: The aims of this study are to analyze differences in survival between academic and non-academic hospitals and to provide insight into treatment patterns for non-small cell lung cancer (NSCLC). Results show the state of NSCLC survival and care in the Netherlands. Methods: The Netherlands Cancer Registry provided data on NSCLC survival for all Dutch hospitals. We used the Kaplan-Meier estimate to calculate median survival time by hospital type and a Cox proportional hazards model to estimate the relative risk of mortality (expressed as hazard ratios) for patients diagnosed in academic versus non-academic hospitals, with adjustment for age, gender, and tumor histology, and stratifying for disease stage. Data on treatment patterns in Dutch hospitals was obtained from 4 hospitals (2 academic, 2 non-academic). A random sample of patients diagnosed with NSCLC from January 2009 until January 2011 was identified through hospital databases. Data was obtained on patient characteristics, tumor characteristics, and treatments. Results: The Cox proportional hazards model shows a significantly decreased hazard ratio of mortality for patients diagnosed in academic hospitals, as opposed to patients diagnosed in non-academic hospitals. This is specifically true for primary radiotherapy patients and patients who receive systemic treatment for non-metastasized NSCLC. Conclusion: Patients diagnosed in academic hospitals have better median overall survival than patients diagnosed in non-academic hospitals, especially for patients treated with radiotherapy, systemic treatment, or combinations. This difference may be ...