More severe parotid gland histopathology in paediatric-onset than in adult-onset Sjögren's disease

OBJECTIVES: The aim of this study was to assess the histopathological features of the parotid glands in patients with paediatric-onset Sjögren's disease (pedSjD) in comparison to patients with adult-onset Sjögren's disease (adSjD). METHODS: This study was performed in Groningen, the Netherlands. Patients with pedSjD from a diagnostic paediatric cohort (n=19), patients with adSjD from a diagnostic adult cohort (n=32) and patients with adSjD who participated in a clinical trial (n=42) with a baseline parotid gland biopsy were included. Parotid gland biopsies were analysed after (immuno)histolo... Mehr ...

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Verfasser: Legger, Geertje Elizabeth
Nakshbandi, Uzma
van Ginkel, Martha S
Liefers, Silvia C
de Wolff, Lisette
Stel, Alja J
Armbrust, Wineke
Spijkervet, Fred K L
Vissink, Arjan
Arends, Suzanne
Bootsma, Hendrika
van der Vegt, Bert
Verstappen, Gwenny M
Kroese, Frans G M
Dokumenttyp: Artikel
Erscheinungsdatum: 2024
Reihe/Periodikum: Legger , G E , Nakshbandi , U , van Ginkel , M S , Liefers , S C , de Wolff , L , Stel , A J , Armbrust , W , Spijkervet , F K L , Vissink , A , Arends , S , Bootsma , H , van der Vegt , B , Verstappen , G M & Kroese , F G M 2024 , ' More severe parotid gland histopathology in paediatric-onset than in adult-onset Sjögren's disease ' , RMD Open , vol. 10 , no. 3 , e004201 . https://doi.org/10.1136/rmdopen-2024-004201
Schlagwörter: Humans / Sjogren's Syndrome/pathology / Female / Male / Parotid Gland/pathology / Child / Adult / Age of Onset / Adolescent / Middle Aged / Severity of Illness Index / Biopsy / Netherlands/epidemiology / Aged / Young Adult / Biomarkers
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29190854
Datenquelle: BASE; Originalkatalog
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Link(s) : https://hdl.handle.net/11370/470a9ea7-39d6-4d82-bc50-c6731b525d8a