Economic evaluation of apixaban for the prevention of stroke in non-valvular atrial fibrillation in the Netherlands

BACKGROUND: Stroke prevention is the main goal of treating patients with atrial fibrillation (AF). Vitamin-K antagonists (VKAs) present an effective treatment in stroke prevention, however, the risk of bleeding and the requirement for regular coagulation monitoring are limiting their use. Apixaban is a novel oral anticoagulant associated with significantly lower hazard rates for stroke, major bleedings and treatment discontinuations, compared to VKAs. OBJECTIVE: To estimate the cost-effectiveness of apixaban compared to VKAs in non-valvular AF patients in the Netherlands. METHODS: Previously p... Mehr ...

Verfasser: Stevanovic, Jelena
Pompen, Marjolein
Le, Hoa H.
Rozenbaum, Mark H.
Tieleman, Robert G.
Postma, Maarten J.
Dokumenttyp: Artikel
Erscheinungsdatum: 2014
Reihe/Periodikum: Stevanovic , J , Pompen , M , Le , H H , Rozenbaum , M H , Tieleman , R G & Postma , M J 2014 , ' Economic evaluation of apixaban for the prevention of stroke in non-valvular atrial fibrillation in the Netherlands ' , PLoS ONE , vol. 9 , no. 8 , e103974 . https://doi.org/10.1371/journal.pone.0103974
Schlagwörter: NCT00412984 / NCT00496769 / acenocoumarol / acetylsalicylic acid / antivitamin K / apixaban / phenprocoumon / warfarin / adult / aged / anticoagulation / article / bleeding / brain hemorrhage / brain ischemia / cerebrovascular accident / clinical article / controlled study / cost effectiveness analysis / diabetes mellitus / drug cost / economic evaluation / female / gastrointestinal hemorrhage / health care cost / heart atrium fibrillation / heart failure / heart infarction / human / hypertension / international normalized ratio / male / Netherlands / non valvular heart atrium fibrillation / quality adjusted life year / quality of life / sensitivity analysis / thromboembolism
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29190454
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://hdl.handle.net/11370/22ccec7f-b1cb-483d-85cf-52029f211bba