Influenza Vaccine Effectiveness in the Netherlands from 2003/2004 through 2013/2014:The Importance of Circulating Influenza Virus Types and Subtypes

Influenza vaccine effectiveness (IVE) varies over different influenza seasons and virus (sub) types/lineages. To assess the association between IVE and circulating influenza virus (sub) types/lineages, we estimated the overall and (sub) type specific IVE in the Netherlands. We conducted a test-negative case control study among subjects with influenza-like illness or acute respiratory tract infection consulting the Sentinel Practices over 11 influenza seasons (2003/2004 through 2013/2014) in the Netherlands. The adjusted IVE was estimated using generalized linear mixed modelling and multiple lo... Mehr ...