Use of anti-depressants and the risk of fracture of the hip or femur
SUMMARY: Anti-depressants are used largely, but have serious side effects. We show that both selective serotonin re-uptake inhibitors (SSRIs) and tricyclic anti-depressants (TCAs) increase the risk of hip/femur fracture and that this risk is time related and depends on the degree of serotonin transporter inhibition. This should be considered when prescribing anti-depressants to patients. INTRODUCTION: Anti-depressants are known to have serious side effects. We examined the association between the use of anti-depressants and the risk of hip/femur fractures with a special focus on the relation w... Mehr ...
| Verfasser: |
van den Brand, M W M
Pouwels, S
Samson, M M
van Staa, T P
Thio, B
Cooper, C
Leufkens, H G M
Egberts, A C G
Verhaar, H J J
de Vries, F |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2009 |
| Reihe/Periodikum: |
van den Brand , M W M , Pouwels , S , Samson , M M , van Staa , T P , Thio , B , Cooper , C , Leufkens , H G M , Egberts , A C G , Verhaar , H J J & de Vries , F 2009 , ' Use of anti-depressants and the risk of fracture of the hip or femur ' , Osteoporosis International , vol. 20 , no. 10 , pp. 1705-13 . https://doi.org/10.1007/s00198-009-0849-6 |
| Schlagwörter: |
Adolescent
/ Adult
/ Aged
/ Antidepressive Agents/administration & dosage
/ Antidepressive Agents
/ Tricyclic/administration & dosage
/ Drug Administration Schedule
/ Epidemiologic Methods
/ Female
/ Femoral Fractures/chemically induced
/ Hip Fractures/chemically induced
/ Humans
/ Male
/ Middle Aged
/ Netherlands/epidemiology
/ Serotonin Uptake Inhibitors/administration & dosage
/ Young Adult |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29187785 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/da944813-d4c9-4bfa-a5ea-7c75ed95ddb7 |
