A genome-wide linkage study of individuals with high scores on NEO personality traits

The NEO-Five-Factor Inventory divides human personality traits into five dimensions: neuroticism, extraversion, openness, conscientiousness and agreeableness. In this study, we sought to identify regions harboring genes with large effects on the five NEO personality traits by performing genome-wide linkage analysis of individuals scoring in the extremes of these traits (>90th percentile). Affected-only linkage analysis was performed using an Illumina 6K linkage array in a family-based study, the Erasmus Rucphen Family study. We subsequently determined whether distinct, segregating haplotype... Mehr ...

Volltext
Verfasser: Amin, N
Schuur, M
Gusareva, E S
Isaacs, A
Aulchenko, Y S
Kirichenko, A V
Zorkoltseva, I V
Axenovich, T I
Oostra, B A
Janssens, A C J W
van Duijn, C M
Dokumenttyp: Artikel
Erscheinungsdatum: 2012
Reihe/Periodikum: Amin , N , Schuur , M , Gusareva , E S , Isaacs , A , Aulchenko , Y S , Kirichenko , A V , Zorkoltseva , I V , Axenovich , T I , Oostra , B A , Janssens , A C J W & van Duijn , C M 2012 , ' A genome-wide linkage study of individuals with high scores on NEO personality traits ' , Molecular Psychiatry , vol. 17 , no. 10 , pp. 1031-41 . https://doi.org/10.1038/mp.2011.97
Schlagwörter: Adolescent / Adult / Aggression/physiology / Anxiety Disorders/genetics / Child / Chromosomes / Human/genetics / Cohort Studies / Consciousness/physiology / DNA Copy Number Variations/genetics / Emotional Intelligence / Extraversion / Psychological / Family Health / Female / Genetic Linkage/genetics / Genome-Wide Association Study/methods / Genotype / Humans / Male / Middle Aged / Netherlands / Neuroticism / Personality/genetics / Personality Inventory / Phenotype / Young Adult
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29187760
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://cris.maastrichtuniversity.nl/en/publications/d67d897f-7509-45a0-9328-f741c01325cb