Personalized management of atrial fibrillation

The management of atrial fibrillation (AF) has seen marked changes in past years, with the introduction of new oral anticoagulants, new antiarrhythmic drugs, and the emergence of catheter ablation as a common intervention for rhythm control. Furthermore, new technologies enhance our ability to detect AF. Most clinical management decisions in AF patients can be based on validated parameters that encompass type of presentation, clinical factors, electrocardiogram analysis, and cardiac imaging. Despite these advances, patients with AF are still at increased risk for death, stroke, heart failure,... Mehr ...

Verfasser: Angelika Leute
James A. Reiffel
A. John Camm
Thorsten Lewalter
Carina Blomström-Lundqvist
Sakis Themistoclakis
Lucas V.A. Boersma
Michael D. Ezekowitz
Ralf Meyer
Ursula Ravens
Anne M. Gillis
David J. Werring
Thomas Fetsch
Barbara Casadei
Ron Pisters
Stéphane N. Hatem
Dobromir Dobrev
Angelo Auricchio
van Isabelle Gelder
Andrea Gerth
Karl Georg Haeusler
Burkert Pieske
Ali Oto
Stavros Apostolakis
Markus Mueller
Helen Brown
Martina Brueckmann
Michele Massimo Gulizia
Gerhard Steinbeck
Tatjana S. Potpara
Alphons Vincent
Felix Muenzel
Karl-Heinz Kuck
Lukas Kappenberger
Hugh Calkins
Laurent M. Haegeli
Karen Thomitzek
Deirdre A. Lane
Guido Hack
Roland Derwand
Axel Brandes
Wim Stegink
Michael Naebauer
Michael Oeff
Sana Al Khatib
Gregory Moses
Luigi Tavazzi
Paulus Kirchhof
Giuseppe Boriani
Etienne Aliot
Isabelle Richard-Lordereau
Christophe Bailleul
Gregory Y.H. Lip
Jessica Hernandez-Brichis
Harry J.G.M. Crijns
Gerlinde Benninger
Andreas Clemens
Jeroen J. Bax
J Kautzner
Berndt von Stritzky
Jens Cosedis Nielsen
Lars Melholt Rasmussen
Pierre Jaïs
Lluís Mont
Stephan Willems
Lukasz Szumowski
Ulrich Schotten
Hein Heidbuechel
Kenneth M. Stein
Steven Kim
Guenter Breithardt
Herbert Schaefer
Dokumenttyp: Artikel
Erscheinungsdatum: 2013
Schlagwörter: Neuroinformatics / Netherlands / Aurora Universities Network / Health / SP1-Cooperation / EBRAINS / EC / FP7 / European Commission / Knowmad Institut / Physiology (medical) / Cardiology and Cardiovascular Medicine
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29181115
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://www.openaccessrepository.it/record/100957

The management of atrial fibrillation (AF) has seen marked changes in past years, with the introduction of new oral anticoagulants, new antiarrhythmic drugs, and the emergence of catheter ablation as a common intervention for rhythm control. Furthermore, new technologies enhance our ability to detect AF. Most clinical management decisions in AF patients can be based on validated parameters that encompass type of presentation, clinical factors, electrocardiogram analysis, and cardiac imaging. Despite these advances, patients with AF are still at increased risk for death, stroke, heart failure, and hospitalizations. During the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association (AFNET/EHRA) consensus conference, we identified the following opportunities to personalize management of AF in a better manner with a view to improve outcomes by integrating atrial morphology and damage, brain imaging, information on genetic predisposition, systemic or local inflammation, and markers for cardiac strain. Each of these promising avenues requires validation in the context of existing risk factors in patients. More importantly, a new taxonomy of AF may be needed based on the pathophysiological type of AF to allow personalized management of AF to come to full fruition. Continued translational research efforts are needed to personalize management of this prevalent disease in a better manner. All the efforts are expected to improve the management of patients with AF based on personalized therapy.