The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples:An NTM-NET collaborative study

A significant knowledge gap exists concerning the geographical distribution of nontuberculous mycobacteria (NTM) isolation worldwide. To provide a snapshot of NTM species distribution, global partners in the NTM-Network European Trials Group (NET) framework (www.ntm-net.org), a branch of the Tuberculosis Network European Trials Group (TB-NET), provided identification results of the total number of patients in 2008 in whom NTM were isolated from pulmonary samples. From these data, we visualised the relative distribution of the different NTM found per continent and per country. We received speci... Mehr ...

Verfasser: Hoefsloot, Wouter
Van Ingen, Jakko
Andrejak, Claire
Angeby, Kristian
Bauriaud, Rosine
Bemer, Pascale
Beylis, Natalie
Boeree, Martin J.
Cacho, Juana
Chihota, Violet
Chimara, Erica
Churchyard, Gavin
Cias, Raquel
Daza, Rosa
Daley, Charles L.
Dekhuijzen, P. N. Richard
Domingo, Diego
Drobniewski, Francis
Esteban, Jaime
Fauvilte-Dufaux, Maryse
Folkvardsen, Dorte Bek
Gibbons, Noel
Gomez-Mampaso, Enrique
Gonzalez, Rosa
Hoffmann, Harald
Hsueh, Po-Ren
Indra, Alexander
Jagielski, Tomasz
Jamieson, Frances
Jankovic, Mateja
Jong, Eefje
Keane, Joseph
Koh, Wo-Jung
Lange, Bent
Leao, Sylvia
Macedo, Rita
Mannsaker, Lurid
Marras, Theodore K.
Maugein, Jeannette
Milburn, Heather
Mlinko, Tannas
Morcillo, Nora
Morimoto, Kozo
Papaventsis, Dimitrios
Palenque, Elia
Paez-Peria, Mar
Piersimoni, Claudio
Polanova, Monika
Rastogi, Nalin
Richter, Elvira
Dokumenttyp: Artikel
Erscheinungsdatum: 2013
Reihe/Periodikum: Hoefsloot , W , Van Ingen , J , Andrejak , C , Angeby , K , Bauriaud , R , Bemer , P , Beylis , N , Boeree , M J , Cacho , J , Chihota , V , Chimara , E , Churchyard , G , Cias , R , Daza , R , Daley , C L , Dekhuijzen , P N R , Domingo , D , Drobniewski , F , Esteban , J , Fauvilte-Dufaux , M , Folkvardsen , D B , Gibbons , N , Gomez-Mampaso , E , Gonzalez , R , Hoffmann , H , Hsueh , P-R , Indra , A , Jagielski , T , Jamieson , F , Jankovic , M , Jong , E , Keane , J , Koh , W-J , Lange , B , Leao , S , Macedo , R , Mannsaker , L , Marras , T K , Maugein , J , Milburn , H , Mlinko , T , Morcillo , N , Morimoto , K , Papaventsis , D , Palenque , E , Paez-Peria , M , Piersimoni , C , Polanova , M , Rastogi , N , Richter , E 2013 , ' The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples : An NTM-NET collaborative study ' , European Respiratory Journal , vol. 42 , no. 6 , pp. 1604-1613 . https://doi.org/10.1183/09031936.00149212
Schlagwörter: CLINICAL-SIGNIFICANCE / GENETIC VARIANT / AVIUM COMPLEX / INFECTIONS / EPIDEMIOLOGY / NETHERLANDS / MALMOENSE / RELEVANCE / KANSASII / PATTERNS
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29178504
Datenquelle: BASE; Originalkatalog
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Link(s) : https://kclpure.kcl.ac.uk/portal/en/publications/the-geographic-diversity-of-nontuberculous-mycobacteria-isolated-from-pulmonary-samples(3c61dd15-1b7d-47ce-b0f8-5cd7eb3eb9c9).html

A significant knowledge gap exists concerning the geographical distribution of nontuberculous mycobacteria (NTM) isolation worldwide. To provide a snapshot of NTM species distribution, global partners in the NTM-Network European Trials Group (NET) framework (www.ntm-net.org), a branch of the Tuberculosis Network European Trials Group (TB-NET), provided identification results of the total number of patients in 2008 in whom NTM were isolated from pulmonary samples. From these data, we visualised the relative distribution of the different NTM found per continent and per country. We received species identification data for 20182 patients, from 62 laboratories in 30 countries across six continents. 91 different NTM species were isolated. Mycobacterium avium complex (MAC) bacteria predominated in most countries, followed by M. gordonae and M. xenopi. Important differences in geographical distribution of MAC species as well as M. xenopi, M. kansasii and rapid-growing mycobacteria were observed. This snapshot demonstrates that the species distribution among NTM isolates from pulmonary specimens in the year 2008 differed by continent and differed by country within these continents. These differences in species distribution may partly determine the frequency and manifestations of pulmonary NTM disease in each geographical location.