Childbirth Moderates the Genetic and Environmental Influences on BMI in Adult Twins
We report a study of the moderating role that the number of childbirths has on the genetic and environmental influences on BMI variation. We used a classical twin design with a sample of 704 adult female twins (334 monozygotic and 370 dizygotic). A gene-environment interaction (G x E) model was applied to estimate the moderating effects of childbearing. Results show that age and number of children exert a significant positive main effect on BMI. Furthermore, we found significant moderating effects of childbearing, with a larger number of children associated with an increased sensitivity to env... Mehr ...
| Verfasser: | |
|---|---|
| Dokumenttyp: | Artikel |
| Erscheinungsdatum: | 2009 |
| Reihe/Periodikum: | Rebollo-Mesa , I & Ordonana , J R 2009 , ' Childbirth Moderates the Genetic and Environmental Influences on BMI in Adult Twins ' , Obesity , vol. 17 , no. 8 , pp. 1646-1647 . https://doi.org/10.1038/oby.2009.108 |
| Schlagwörter: | BODY-MASS INDEX / PHYSICAL-ACTIVITY / WEIGHT RETENTION / ASSOCIATION / PREGNANCY / FAT / HERITABILITY / NETHERLANDS / PARITY / YOUNG |
| Sprache: | Englisch |
| Permalink: | https://search.fid-benelux.de/Record/base-29178474 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://kclpure.kcl.ac.uk/portal/en/publications/57df3884-72a2-47c1-9b73-aed5adb1ce7a |
We report a study of the moderating role that the number of childbirths has on the genetic and environmental influences on BMI variation. We used a classical twin design with a sample of 704 adult female twins (334 monozygotic and 370 dizygotic). A gene-environment interaction (G x E) model was applied to estimate the moderating effects of childbearing. Results show that age and number of children exert a significant positive main effect on BMI. Furthermore, we found significant moderating effects of childbearing, with a larger number of children associated with an increased sensitivity to environmental factors.