Political participation is an important aspect of the integration of Muslim citizens into western societies. However, Muslims’ formal political participation is often met with resistance from the majority population. In two studies, we investigated among national samples of majority Dutch whether the level of resistance to the democratic political organizations of Muslim citizens is associated with political orientation and level of education. Furthermore, we examined whether these associations are mediated by the endorsement of multiculturalism. Findings from both studies show that the higher educated and politically left-wing individuals are more supportive of Muslim political organisation and that this association is (partly) explained by the endorsement of multiculturalism. Additionally, in Study 2 it is found that attitudes toward cultural tradition and group equality mediate the relations between education and political orientation with multiculturalism.