Improved survival of colon cancer due to improved treatment and detection: a nationwide population-based study in The Netherlands 1989-2006

Background: We described changes in treatment of colon cancer over time and the impact on survival in The Netherlands in the period 1989–2006. Patients and methods: All 103 744 patients with invasive colon cancer during 1989–2006 in The Netherlands were included. Data were extracted from The Netherlands Cancer Registry. Trends in treatment over time were analysed and multivariable relative survival analysis was carried out. Results: The administration of adjuvant chemotherapy in stage III patients <75 years increased from 19% in 1989–1993 to 79% in 2004–2006 and from 1% to 19% in stage III... Mehr ...