An evidence synthesis approach to estimating the incidence of symptomatic pertussis infection in the Netherlands, 2005–2011 ...

Abstract Background Despite high vaccination coverage, infection with Bordetella pertussis is a current public health concern in the Netherlands and other European Union member states. Because surveillance data are subject to extensive under-ascertainment and under-reporting, incidence is difficult to determine. Our objective was to estimate the age-group specific incidence of symptomatic pertussis infection in the Netherlands over the period 2005–2011, using multi-parameter evidence synthesis. Methods Age-specific seroconversion probabilities were estimated for 2007 using Netherlands populati... Mehr ...