Ulipristal acetate for pre-operative treatment of moderate to severe uterine fibroids in women of reproductive age in The Netherlands: cost minimization analysis and budget impact analysis ...

Objective: Ulipristal acetate has been found to be non-inferior to other pre-operative treatments of uterine fibroids, particularly leuprolide. The objective of this study was to assess the pharmacoeconomic profile of ulipristal acetate compared to leuprolide for the pre-operative treatment of moderate to severe uterine fibroids in women of reproductive age in The Netherlands. The analysis was performed and applied within the framework of the ulipristal acetate submission for reimbursement in 2012. Methods : A decision model was developed to compare the total costs of ulipristal acetate compar... Mehr ...