Decrease in Prevalence of Cleft lip, Alveolus and Palate After Nationwide Introduction of the Second-Trimester Anomaly Scan in the Netherlands ...
OBJECTIVESome studies have suggested that introducing a second-trimester anomaly scan (SAS) leads to increased rates of termination of pregnancy (TOP) in fetuses with orofacial clefts (OFCs). The aim of this study was to evaluate the impact of a nationwide introduction of SAS on the prevalence of live births with OFCs in the Netherlands.DESIGNRetrospective cohort study.SETTINGTertiary setting.POPULATIONIncluded in the study were all patients diagnosed with OFCs as recorded in the “Dutch Association for Cleft Palate Anomalies” database between 1997 and 2019.INTERVENTIONSPatients were divided in... Mehr ...
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| Dokumenttyp: | Datenquelle |
| Erscheinungsdatum: | 2023 |
| Verlag/Hrsg.: |
SAGE Journals
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| Schlagwörter: | 110323 Surgery / FOS: Clinical medicine |
| Sprache: | unknown |
| Permalink: | https://search.fid-benelux.de/Record/base-29160841 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://dx.doi.org/10.25384/sage.c.6366975.v1 |
OBJECTIVESome studies have suggested that introducing a second-trimester anomaly scan (SAS) leads to increased rates of termination of pregnancy (TOP) in fetuses with orofacial clefts (OFCs). The aim of this study was to evaluate the impact of a nationwide introduction of SAS on the prevalence of live births with OFCs in the Netherlands.DESIGNRetrospective cohort study.SETTINGTertiary setting.POPULATIONIncluded in the study were all patients diagnosed with OFCs as recorded in the “Dutch Association for Cleft Palate Anomalies” database between 1997 and 2019.INTERVENTIONSPatients were divided into three categories: cleft lip with or without alveolus (CL/A), cleft lip, alveolus and palate (CLAP) and cleft palate (CP) based on anatomical landmarks at the first consultation.MAIN OUTCOME MEASURESPrevalence rates of OFCs before and after the nationwide introduction of the SAS on January 1, 2007 were compared.RESULTSOverall, 1899 patients were diagnosed with CL/A, 2586 with CLAP and 2927 with CP. The prevalence of ...